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Disease variants alter transcription factor levels and methylation of their binding sites.
Bonder MJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, van der Breggen R, van Rooij J, Lakenberg N, Arindrarto W, Kielbasa SM, Jonkers I, van 't Hof P, Nooren I, Beekman M, Deelen J, van Heemst D, Zhernakova A, Tigchelaar EF, Swertz MA, Hofman A, Uitterlinden AG, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, van den Berg LH, van Zwet EW, Mei H, Li Y, Lemire M, Hudson TJ; BIOS Consortium; Slagboom PE, Wijmenga C, Veldink JH, van Greevenbroek MM, van Duijn CM, Boomsma DI, Isaacs A, Jansen R, van Meurs JB, 't Hoen PA, Franke L, Heijmans BT. Bonder MJ, et al. Among authors: slieker rc. Nat Genet. 2017 Jan;49(1):131-138. doi: 10.1038/ng.3721. Epub 2016 Dec 5. Nat Genet. 2017. PMID: 27918535
Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array.
Slieker RC, Bos SD, Goeman JJ, Bovée JV, Talens RP, van der Breggen R, Suchiman HE, Lameijer EW, Putter H, van den Akker EB, Zhang Y, Jukema JW, Slagboom PE, Meulenbelt I, Heijmans BT. Slieker RC, et al. Epigenetics Chromatin. 2013 Aug 6;6(1):26. doi: 10.1186/1756-8935-6-26. Epigenetics Chromatin. 2013. PMID: 23919675 Free PMC article.
DNA methylation signatures link prenatal famine exposure to growth and metabolism.
Tobi EW, Goeman JJ, Monajemi R, Gu H, Putter H, Zhang Y, Slieker RC, Stok AP, Thijssen PE, Müller F, van Zwet EW, Bock C, Meissner A, Lumey LH, Eline Slagboom P, Heijmans BT. Tobi EW, et al. Among authors: slieker rc. Nat Commun. 2014 Nov 26;5:5592. doi: 10.1038/ncomms6592. Nat Commun. 2014. PMID: 25424739 Free PMC article.
Corrigendum: DNA methylation signatures link prenatal famine exposure to growth and metabolism.
Tobi EW, Goeman JJ, Monajemi R, Gu H, Putter H, Zhang Y, Slieker RC, Stok AP, Thijssen PE, Müller F, van Zwet EW, Bock C, Meissner A, Lumey LH, Eline Slagboom P, Heijmans BT. Tobi EW, et al. Among authors: slieker rc. Nat Commun. 2015 Jul 7;6:7740. doi: 10.1038/ncomms8740. Nat Commun. 2015. PMID: 26151124 Free PMC article. No abstract available.
DNA Methylation Landscapes of Human Fetal Development.
Slieker RC, Roost MS, van Iperen L, Suchiman HE, Tobi EW, Carlotti F, de Koning EJ, Slagboom PE, Heijmans BT, Chuva de Sousa Lopes SM. Slieker RC, et al. PLoS Genet. 2015 Oct 22;11(10):e1005583. doi: 10.1371/journal.pgen.1005583. eCollection 2015 Oct. PLoS Genet. 2015. PMID: 26492326 Free PMC article.
Neo-cartilage engineered from primary chondrocytes is epigenetically similar to autologous cartilage, in contrast to using mesenchymal stem cells.
Bomer N, den Hollander W, Suchiman H, Houtman E, Slieker RC, Heijmans BT, Slagboom PE, Nelissen RG, Ramos YF, Meulenbelt I. Bomer N, et al. Among authors: slieker rc. Osteoarthritis Cartilage. 2016 Aug;24(8):1423-30. doi: 10.1016/j.joca.2016.03.009. Epub 2016 Mar 17. Osteoarthritis Cartilage. 2016. PMID: 26995110 Free article.
81 results