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Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting.
Slaney CY, von Scheidt B, Davenport AJ, Beavis PA, Westwood JA, Mardiana S, Tscharke DC, Ellis S, Prince HM, Trapani JA, Johnstone RW, Smyth MJ, Teng MW, Ali A, Yu Z, Rosenberg SA, Restifo NP, Neeson P, Darcy PK, Kershaw MH. Slaney CY, et al. Clin Cancer Res. 2017 May 15;23(10):2478-2490. doi: 10.1158/1078-0432.CCR-16-1860. Epub 2016 Dec 13. Clin Cancer Res. 2017. PMID: 27965307 Free PMC article.
A Multifunctional Role for Adjuvant Anti-4-1BB Therapy in Augmenting Antitumor Response by Chimeric Antigen Receptor T Cells.
Mardiana S, John LB, Henderson MA, Slaney CY, von Scheidt B, Giuffrida L, Davenport AJ, Trapani JA, Neeson PJ, Loi S, Haynes NM, Kershaw MH, Beavis PA, Darcy PK. Mardiana S, et al. Among authors: slaney cy. Cancer Res. 2017 Mar 15;77(6):1296-1309. doi: 10.1158/0008-5472.CAN-16-1831. Epub 2017 Jan 12. Cancer Res. 2017. PMID: 28082401
Enterotoxins can support CAR T cells against solid tumors.
von Scheidt B, Wang M, Oliver AJ, Chan JD, Jana MK, Ali AI, Clow F, Fraser JD, Quinn KM, Darcy PK, Kershaw MH, Slaney CY. von Scheidt B, et al. Among authors: slaney cy. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25229-25235. doi: 10.1073/pnas.1904618116. Epub 2019 Nov 25. Proc Natl Acad Sci U S A. 2019. PMID: 31767744 Free PMC article.
Tissue-specific tumor microenvironments influence responses to immunotherapies.
Oliver AJ, Davey AS, Keam SP, Mardiana S, Chan JD, von Scheidt B, Beavis PA, House IG, Van Audernaerde JR, Darcy PK, Kershaw MH, Slaney CY. Oliver AJ, et al. Among authors: slaney cy. Clin Transl Immunology. 2019 Nov 21;8(11):e1094. doi: 10.1002/cti2.1094. eCollection 2019. Clin Transl Immunology. 2019. PMID: 31768254 Free PMC article.
Enhancing chimeric antigen receptor T-cell immunotherapy against cancer using a nanoemulsion-based vaccine targeting cross-presenting dendritic cells.
Chan JD, von Scheidt B, Zeng B, Oliver AJ, Davey AS, Ali AI, Thomas R, Trapani JA, Darcy PK, Kershaw MH, Dolcetti R, Slaney CY. Chan JD, et al. Among authors: slaney cy. Clin Transl Immunology. 2020 Jul 22;9(7):e1157. doi: 10.1002/cti2.1157. eCollection 2020. Clin Transl Immunology. 2020. PMID: 32704371 Free PMC article.
Novel combination immunotherapy for pancreatic cancer: potent anti-tumor effects with CD40 agonist and interleukin-15 treatment.
Van Audenaerde JR, Marcq E, von Scheidt B, Davey AS, Oliver AJ, De Waele J, Quatannens D, Van Loenhout J, Pauwels P, Roeyen G, Lardon F, Slaney CY, Peeters M, Kershaw MH, Darcy PK, Smits EL. Van Audenaerde JR, et al. Among authors: slaney cy. Clin Transl Immunology. 2020 Aug 15;9(8):e1165. doi: 10.1002/cti2.1165. eCollection 2020. Clin Transl Immunology. 2020. PMID: 32821382 Free PMC article.
45 results