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PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.
Appel LM, Franke V, Bruno M, Grishkovskaya I, Kasiliauskaite A, Kaufmann T, Schoeberl UE, Puchinger MG, Kostrhon S, Ebenwaldner C, Sebesta M, Beltzung E, Mechtler K, Lin G, Vlasova A, Leeb M, Pavri R, Stark A, Akalin A, Stefl R, Bernecky C, Djinovic-Carugo K, Slade D. Appel LM, et al. Among authors: slade d. Nat Commun. 2021 Oct 19;12(1):6078. doi: 10.1038/s41467-021-26360-2. Nat Commun. 2021. PMID: 34667177 Free PMC article.
SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation.
Kaufmann T, Kukolj E, Brachner A, Beltzung E, Bruno M, Kostrhon S, Opravil S, Hudecz O, Mechtler K, Warren G, Slade D. Kaufmann T, et al. Among authors: slade d. J Cell Sci. 2016 Dec 15;129(24):4607-4621. doi: 10.1242/jcs.192633. Epub 2016 Nov 14. J Cell Sci. 2016. PMID: 27875273 Free PMC article.
A novel non-canonical PIP-box mediates PARG interaction with PCNA.
Kaufmann T, Grishkovskaya I, Polyansky AA, Kostrhon S, Kukolj E, Olek KM, Herbert S, Beltzung E, Mechtler K, Peterbauer T, Gotzmann J, Zhang L, Hartl M, Zagrovic B, Elsayad K, Djinovic-Carugo K, Slade D. Kaufmann T, et al. Among authors: slade d. Nucleic Acids Res. 2017 Sep 19;45(16):9741-9759. doi: 10.1093/nar/gkx604. Nucleic Acids Res. 2017. PMID: 28934471 Free PMC article.
PARP inhibition causes premature loss of cohesion in cancer cells.
Kukolj E, Kaufmann T, Dick AE, Zeillinger R, Gerlich DW, Slade D. Kukolj E, et al. Among authors: slade d. Oncotarget. 2017 Oct 16;8(61):103931-103951. doi: 10.18632/oncotarget.21879. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262611 Free PMC article.
The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Appel LM, Franke V, Benedum J, Grishkovskaya I, Strobl X, Polyansky A, Ammann G, Platzer S, Neudolt A, Wunder A, Walch L, Kaiser S, Zagrovic B, Djinovic-Carugo K, Akalin A, Slade D. Appel LM, et al. Among authors: slade d. Nat Commun. 2023 Jan 11;14(1):166. doi: 10.1038/s41467-023-35853-1. Nat Commun. 2023. PMID: 36631525 Free PMC article.
269 results