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Ryanodine receptor fragmentation and sarcoplasmic reticulum Ca2+ leak after one session of high-intensity interval exercise.
Place N, Ivarsson N, Venckunas T, Neyroud D, Brazaitis M, Cheng AJ, Ochala J, Kamandulis S, Girard S, Volungevičius G, Paužas H, Mekideche A, Kayser B, Martinez-Redondo V, Ruas JL, Bruton J, Truffert A, Lanner JT, Skurvydas A, Westerblad H. Place N, et al. Among authors: skurvydas a. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15492-7. doi: 10.1073/pnas.1507176112. Epub 2015 Nov 2. Proc Natl Acad Sci U S A. 2015. PMID: 26575622 Free PMC article. Clinical Trial.
Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans.
Schlittler M, Goiny M, Agudelo LZ, Venckunas T, Brazaitis M, Skurvydas A, Kamandulis S, Ruas JL, Erhardt S, Westerblad H, Andersson DC. Schlittler M, et al. Among authors: skurvydas a. Am J Physiol Cell Physiol. 2016 May 15;310(10):C836-40. doi: 10.1152/ajpcell.00053.2016. Epub 2016 Mar 30. Am J Physiol Cell Physiol. 2016. PMID: 27030575 Free article. Clinical Trial.
Prolonged force depression after mechanically demanding contractions is largely independent of Ca2+ and reactive oxygen species.
Kamandulis S, de Souza Leite F, Hernández A, Katz A, Brazaitis M, Bruton JD, Venckunas T, Masiulis N, Mickeviciene D, Eimantas N, Subocius A, Rassier DE, Skurvydas A, Ivarsson N, Westerblad H. Kamandulis S, et al. Among authors: skurvydas a. FASEB J. 2017 Nov;31(11):4809-4820. doi: 10.1096/fj.201700019R. Epub 2017 Jul 17. FASEB J. 2017. PMID: 28716970
In conclusion, PLFFD caused by mechanically demanding eccentric contractions does not involve any major increase in ROS or RyR1 fragmentation.-Kamandulis, S., de Souza Leite, F., Hernandez, A., Katz, A., Brazaitis, M., Bruton, J. D., Venckunas, T., Masiulis, N., Mic …
In conclusion, PLFFD caused by mechanically demanding eccentric contractions does not involve any major increase in ROS or RyR1 fragmentatio …
Three weeks of sprint interval training improved high-intensity cycling performance and limited ryanodine receptor modifications in recreationally active human subjects.
Schlittler M, Neyroud D, Tanga C, Zanou N, Kamandulis S, Skurvydas A, Kayser B, Westerblad H, Place N, Andersson DC. Schlittler M, et al. Among authors: skurvydas a. Eur J Appl Physiol. 2019 Sep;119(9):1951-1958. doi: 10.1007/s00421-019-04183-w. Epub 2019 Jun 27. Eur J Appl Physiol. 2019. PMID: 31250088
129 results