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Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity.
Iyer KR, Li SC, Revie NM, Lou JW, Duncan D, Fallah S, Sanchez H, Skulska I, Ušaj MM, Safizadeh H, Larsen B, Wong C, Aman A, Kiyota T, Yoshimura M, Kimura H, Hirano H, Yoshida M, Osada H, Gingras AC, Andes DR, Shapiro RS, Robbins N, Mazhab-Jafari MT, Whitesell L, Yashiroda Y, Boone C, Cowen LE. Iyer KR, et al. Among authors: skulska i. Cell Chem Biol. 2023 Jul 20;30(7):795-810.e8. doi: 10.1016/j.chembiol.2023.06.005. Epub 2023 Jun 26. Cell Chem Biol. 2023. PMID: 37369212 Free PMC article.
Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation.
Revie NM, Iyer KR, Maxson ME, Zhang J, Yan S, Fernandes CM, Meyer KJ, Chen X, Skulska I, Fogal M, Sanchez H, Hossain S, Li S, Yashiroda Y, Hirano H, Yoshida M, Osada H, Boone C, Shapiro RS, Andes DR, Wright GD, Nodwell JR, Del Poeta M, Burke MD, Whitesell L, Robbins N, Cowen LE. Revie NM, et al. Among authors: skulska i. Nat Commun. 2022 Jun 25;13(1):3634. doi: 10.1038/s41467-022-31308-1. Nat Commun. 2022. PMID: 35752611 Free PMC article.