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Page 1
An attempt to prevent senescence: a mitochondrial approach.
Skulachev VP, Anisimov VN, Antonenko YN, Bakeeva LE, Chernyak BV, Erichev VP, Filenko OF, Kalinina NI, Kapelko VI, Kolosova NG, Kopnin BP, Korshunova GA, Lichinitser MR, Obukhova LA, Pasyukova EG, Pisarenko OI, Roginsky VA, Ruuge EK, Senin II, Severina II, Skulachev MV, Spivak IM, Tashlitsky VN, Tkachuk VA, Vyssokikh MY, Yaguzhinsky LS, Zorov DB. Skulachev VP, et al. Among authors: skulachev mv. Biochim Biophys Acta. 2009 May;1787(5):437-61. doi: 10.1016/j.bbabio.2008.12.008. Epub 2008 Dec 29. Biochim Biophys Acta. 2009. PMID: 19159610 Free article. Review.
Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: synthesis and in vitro studies.
Antonenko YN, Avetisyan AV, Bakeeva LE, Chernyak BV, Chertkov VA, Domnina LV, Ivanova OY, Izyumov DS, Khailova LS, Klishin SS, Korshunova GA, Lyamzaev KG, Muntyan MS, Nepryakhina OK, Pashkovskaya AA, Pletjushkina OY, Pustovidko AV, Roginsky VA, Rokitskaya TI, Ruuge EK, Saprunova VB, Severina II, Simonyan RA, Skulachev IV, Skulachev MV, Sumbatyan NV, Sviryaeva IV, Tashlitsky VN, Vassiliev JM, Vyssokikh MY, Yaguzhinsky LS, Zamyatnin AA Jr, Skulachev VP. Antonenko YN, et al. Among authors: skulachev vp, skulachev mv, skulachev iv. Biochemistry (Mosc). 2008 Dec;73(12):1273-87. doi: 10.1134/s0006297908120018. Biochemistry (Mosc). 2008. PMID: 19120014 Free article.
Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 2. Treatment of some ROS- and age-related diseases (heart arrhythmia, heart infarctions, kidney ischemia, and stroke).
Bakeeva LE, Barskov IV, Egorov MV, Isaev NK, Kapelko VI, Kazachenko AV, Kirpatovsky VI, Kozlovsky SV, Lakomkin VL, Levina SB, Pisarenko OI, Plotnikov EY, Saprunova VB, Serebryakova LI, Skulachev MV, Stelmashook EV, Studneva IM, Tskitishvili OV, Vasilyeva AK, Victorov IV, Zorov DB, Skulachev VP. Bakeeva LE, et al. Among authors: skulachev vp, skulachev mv. Biochemistry (Mosc). 2008 Dec;73(12):1288-99. doi: 10.1134/s000629790812002x. Biochemistry (Mosc). 2008. PMID: 19120015 Free article.
Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 3. Inhibitory effect of SkQ1 on tumor development from p53-deficient cells.
Agapova LS, Chernyak BV, Domnina LV, Dugina VB, Efimenko AY, Fetisova EK, Ivanova OY, Kalinina NI, Khromova NV, Kopnin BP, Kopnin PB, Korotetskaya MV, Lichinitser MR, Lukashev AL, Pletjushkina OY, Popova EN, Skulachev MV, Shagieva GS, Stepanova EV, Titova EV, Tkachuk VA, Vasiliev JM, Skulachev VP. Agapova LS, et al. Among authors: skulachev vp, skulachev mv. Biochemistry (Mosc). 2008 Dec;73(12):1300-16. doi: 10.1134/s0006297908120031. Biochemistry (Mosc). 2008. PMID: 19120016 Free article.
Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 4. Age-related eye disease. SkQ1 returns vision to blind animals.
Neroev VV, Archipova MM, Bakeeva LE, Fursova AZh, Grigorian EN, Grishanova AY, Iomdina EN, Ivashchenko ZhN, Katargina LA, Khoroshilova-Maslova IP, Kilina OV, Kolosova NG, Kopenkin EP, Korshunov SS, Kovaleva NA, Novikova YP, Philippov PP, Pilipenko DI, Robustova OV, Saprunova VB, Senin II, Skulachev MV, Sotnikova LF, Stefanova NA, Tikhomirova NK, Tsapenko IV, Shchipanova AI, Zinovkin RA, Skulachev VP. Neroev VV, et al. Among authors: skulachev vp, skulachev mv. Biochemistry (Mosc). 2008 Dec;73(12):1317-28. doi: 10.1134/s0006297908120043. Biochemistry (Mosc). 2008. PMID: 19120017 Free article.
Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 5. SkQ1 prolongs lifespan and prevents development of traits of senescence.
Anisimov VN, Bakeeva LE, Egormin PA, Filenko OF, Isakova EF, Manskikh VN, Mikhelson VM, Panteleeva AA, Pasyukova EG, Pilipenko DI, Piskunova TS, Popovich IG, Roshchina NV, Rybina OY, Saprunova VB, Samoylova TA, Semenchenko AV, Skulachev MV, Spivak IM, Tsybul'ko EA, Tyndyk ML, Vyssokikh MY, Yurova MN, Zabezhinsky MA, Skulachev VP. Anisimov VN, et al. Among authors: skulachev vp, skulachev mv. Biochemistry (Mosc). 2008 Dec;73(12):1329-42. doi: 10.1134/s0006297908120055. Biochemistry (Mosc). 2008. PMID: 19120018 Free article.
Penetrating cation/fatty acid anion pair as a mitochondria-targeted protonophore.
Severin FF, Severina II, Antonenko YN, Rokitskaya TI, Cherepanov DA, Mokhova EN, Vyssokikh MY, Pustovidko AV, Markova OV, Yaguzhinsky LS, Korshunova GA, Sumbatyan NV, Skulachev MV, Skulachev VP. Severin FF, et al. Among authors: skulachev vp, skulachev mv. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):663-8. doi: 10.1073/pnas.0910216107. Epub 2009 Dec 18. Proc Natl Acad Sci U S A. 2010. PMID: 20080732 Free PMC article.
Prevention of cardiolipin oxidation and fatty acid cycling as two antioxidant mechanisms of cationic derivatives of plastoquinone (SkQs).
Skulachev VP, Antonenko YN, Cherepanov DA, Chernyak BV, Izyumov DS, Khailova LS, Klishin SS, Korshunova GA, Lyamzaev KG, Pletjushkina OY, Roginsky VA, Rokitskaya TI, Severin FF, Severina II, Simonyan RA, Skulachev MV, Sumbatyan NV, Sukhanova EI, Tashlitsky VN, Trendeleva TA, Vyssokikh MY, Zvyagilskaya RA. Skulachev VP, et al. Among authors: skulachev mv. Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):878-89. doi: 10.1016/j.bbabio.2010.03.015. Epub 2010 Mar 20. Biochim Biophys Acta. 2010. PMID: 20307489 Free article. Review.
Mitochondrial-targeted plastoquinone derivatives. Effect on senescence and acute age-related pathologies.
Skulachev MV, Antonenko YN, Anisimov VN, Chernyak BV, Cherepanov DA, Chistyakov VA, Egorov MV, Kolosova NG, Korshunova GA, Lyamzaev KG, Plotnikov EY, Roginsky VA, Savchenko AY, Severina II, Severin FF, Shkurat TP, Tashlitsky VN, Shidlovsky KM, Vyssokikh MY, Zamyatnin AA Jr, Zorov DB, Skulachev VP. Skulachev MV, et al. Among authors: skulachev vp. Curr Drug Targets. 2011 Jun;12(6):800-26. doi: 10.2174/138945011795528859. Curr Drug Targets. 2011. PMID: 21269268 Review.
Novel mitochondria-targeted antioxidants: plastoquinone conjugated with cationic plant alkaloids berberine and palmatine.
Lyamzaev KG, Pustovidko AV, Simonyan RA, Rokitskaya TI, Domnina LV, Ivanova OY, Severina II, Sumbatyan NV, Korshunova GA, Tashlitsky VN, Roginsky VA, Antonenko YN, Skulachev MV, Chernyak BV, Skulachev VP. Lyamzaev KG, et al. Among authors: skulachev vp, skulachev mv. Pharm Res. 2011 Nov;28(11):2883-95. doi: 10.1007/s11095-011-0504-8. Epub 2011 Jun 14. Pharm Res. 2011. PMID: 21671134
54 results