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Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's disease.
Eur J Med Chem. 2023 Dec 5;261:115832. doi: 10.1016/j.ejmech.2023.115832. Epub 2023 Oct 7.
Eur J Med Chem. 2023.
PMID: 37837674
Free article.
8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases.
Knez D, Diez-Iriepa D, Chioua M, Gottinger A, Denic M, Chantegreil F, Nachon F, Brazzolotto X, Skrzypczak-Wiercioch A, Meden A, Pišlar A, Kos J, Žakelj S, Stojan J, Sałat K, Serrano J, Fernández AP, Sánchez-García A, Martínez-Murillo R, Binda C, López-Muñoz F, Gobec S, Marco-Contelles J.
Knez D, et al. Among authors: skrzypczak wiercioch a.
Acta Pharm Sin B. 2023 May;13(5):2152-2175. doi: 10.1016/j.apsb.2023.01.013. Epub 2023 Jan 19.
Acta Pharm Sin B. 2023.
PMID: 37250172
Free PMC article.
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Discovery of new, highly potent and selective inhibitors of BuChE - design, synthesis, in vitro and in vivo evaluation and crystallography studies.
Panek D, Pasieka A, Latacz G, Zaręba P, Szczęch M, Godyń J, Chantegreil F, Nachon F, Brazzolotto X, Skrzypczak-Wiercioch A, Walczak M, Smolik M, Sałat K, Höfner G, Wanner K, Więckowska A, Malawska B.
Panek D, et al. Among authors: skrzypczak wiercioch a.
Eur J Med Chem. 2023 Mar 5;249:115135. doi: 10.1016/j.ejmech.2023.115135. Epub 2023 Jan 18.
Eur J Med Chem. 2023.
PMID: 36696766
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Lipopolysaccharide-Induced Model of Neuroinflammation: Mechanisms of Action, Research Application and Future Directions for Its Use.
Skrzypczak-Wiercioch A, Sałat K.
Skrzypczak-Wiercioch A, et al.
Molecules. 2022 Aug 26;27(17):5481. doi: 10.3390/molecules27175481.
Molecules. 2022.
PMID: 36080253
Free PMC article.
Review.
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