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The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis.
Stoup N, Liberelle M, Schulz C, Cavdarli S, Vasseur R, Magnez R, Lahdaoui F, Skrypek N, Peretti F, Frénois F, Thuru X, Melnyk P, Renault N, Jonckheere N, Lebègue N, Van Seuningen I. Stoup N, et al. Among authors: skrypek n. Cancers (Basel). 2021 Nov 16;13(22):5746. doi: 10.3390/cancers13225746. Cancers (Basel). 2021. PMID: 34830899 Free PMC article.
Mucins and pancreatic cancer.
Jonckheere N, Skrypek N, Van Seuningen I. Jonckheere N, et al. Among authors: skrypek n. Cancers (Basel). 2010 Oct 25;2(4):1794-812. doi: 10.3390/cancers2041794. Cancers (Basel). 2010. PMID: 24281201 Free PMC article.
The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways.
Jonckheere N, Skrypek N, Merlin J, Dessein AF, Dumont P, Leteurtre E, Harris A, Desseyn JL, Susini C, Frénois F, Van Seuningen I. Jonckheere N, et al. Among authors: skrypek n. PLoS One. 2012;7(2):e32232. doi: 10.1371/journal.pone.0032232. Epub 2012 Feb 29. PLoS One. 2012. PMID: 22393391 Free PMC article.
Membrane-bound mucin modular domains: from structure to function.
Jonckheere N, Skrypek N, Frénois F, Van Seuningen I. Jonckheere N, et al. Among authors: skrypek n. Biochimie. 2013 Jun;95(6):1077-86. doi: 10.1016/j.biochi.2012.11.005. Epub 2012 Nov 20. Biochimie. 2013. PMID: 23178705 Free article. Review.
The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-κB and RalB signaling pathways.
Vasseur R, Skrypek N, Duchêne B, Renaud F, Martínez-Maqueda D, Vincent A, Porchet N, Van Seuningen I, Jonckheere N. Vasseur R, et al. Among authors: skrypek n. Biochim Biophys Acta. 2015 Dec;1849(12):1375-84. doi: 10.1016/j.bbagrm.2015.10.014. Epub 2015 Oct 22. Biochim Biophys Acta. 2015. PMID: 26477488
Mucins and tumor resistance to chemotherapeutic drugs.
Jonckheere N, Skrypek N, Van Seuningen I. Jonckheere N, et al. Among authors: skrypek n. Biochim Biophys Acta. 2014 Aug;1846(1):142-51. doi: 10.1016/j.bbcan.2014.04.008. Epub 2014 Apr 29. Biochim Biophys Acta. 2014. PMID: 24785432 Review.
Overexpression of chemokine receptor CXCR2 and ligand CXCL7 in liver metastases from colon cancer is correlated to shorter disease-free and overall survival.
Desurmont T, Skrypek N, Duhamel A, Jonckheere N, Millet G, Leteurtre E, Gosset P, Duchene B, Ramdane N, Hebbar M, Van Seuningen I, Pruvot FR, Huet G, Truant S. Desurmont T, et al. Among authors: skrypek n. Cancer Sci. 2015 Mar;106(3):262-9. doi: 10.1111/cas.12603. Epub 2015 Mar 5. Cancer Sci. 2015. PMID: 25580640 Free PMC article.
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