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The novel lncRNA BlackMamba controls the neoplastic phenotype of ALK- anaplastic large cell lymphoma by regulating the DNA helicase HELLS.
Fragliasso V, Verma A, Manzotti G, Tameni A, Bareja R, Heavican TB, Iqbal J, Wang R, Fiore D, Mularoni V, Chan WC, Lhoumaud P, Skok J, Zanetti E, Merli F, Ciarrocchi A, Elemento O, Inghirami G. Fragliasso V, et al. Among authors: skok j. Leukemia. 2020 Nov;34(11):2964-2980. doi: 10.1038/s41375-020-0754-8. Epub 2020 Mar 2. Leukemia. 2020. PMID: 32123306
DNA methylation disruption reshapes the hematopoietic differentiation landscape.
Izzo F, Lee SC, Poran A, Chaligne R, Gaiti F, Gross B, Murali RR, Deochand SD, Ang C, Jones PW, Nam AS, Kim KT, Kothen-Hill S, Schulman RC, Ki M, Lhoumaud P, Skok JA, Viny AD, Levine RL, Kenigsberg E, Abdel-Wahab O, Landau DA. Izzo F, et al. Nat Genet. 2020 Apr;52(4):378-387. doi: 10.1038/s41588-020-0595-4. Epub 2020 Mar 23. Nat Genet. 2020. PMID: 32203468 Free PMC article.
Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms.
Mullenders J, Aranda-Orgilles B, Lhoumaud P, Keller M, Pae J, Wang K, Kayembe C, Rocha PP, Raviram R, Gong Y, Premsrirut PK, Tsirigos A, Bonneau R, Skok JA, Cimmino L, Hoehn D, Aifantis I. Mullenders J, et al. Among authors: skok ja. J Exp Med. 2015 Oct 19;212(11):1833-50. doi: 10.1084/jem.20151323. Epub 2015 Oct 5. J Exp Med. 2015. PMID: 26438359 Free PMC article.
Brain and cancer associated binding domain mutations provide insight into CTCF's relationship with chromatin and its ability to act as a chromatin organizer.
Do C, Jiang G, Cova G, Katsifis CC, Narducci DN, Yang J, Sakellaropoulos T, Vidal R, Lhoumaud P, Fara Regis F, Kakabadze N, Nora EP, Noyes M, Cheng X, Hansen AS, Skok JA. Do C, et al. Among authors: skok ja. bioRxiv [Preprint]. 2024 Feb 5:2024.01.11.575070. doi: 10.1101/2024.01.11.575070. bioRxiv. 2024. PMID: 38370764 Free PMC article. Preprint.
CTCF and CTCFL in cancer.
Debaugny RE, Skok JA. Debaugny RE, et al. Curr Opin Genet Dev. 2020 Apr;61:44-52. doi: 10.1016/j.gde.2020.02.021. Epub 2020 Apr 22. Curr Opin Genet Dev. 2020. PMID: 32334335 Free PMC article. Review.
115 results