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Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis.
Skendros P, Mitsios A, Chrysanthopoulou A, Mastellos DC, Metallidis S, Rafailidis P, Ntinopoulou M, Sertaridou E, Tsironidou V, Tsigalou C, Tektonidou M, Konstantinidis T, Papagoras C, Mitroulis I, Germanidis G, Lambris JD, Ritis K. Skendros P, et al. J Clin Invest. 2020 Nov 2;130(11):6151-6157. doi: 10.1172/JCI141374. J Clin Invest. 2020. PMID: 32759504 Free PMC article. Clinical Trial.
Tissue factor expression in neutrophil extracellular traps and neutrophil derived microparticles in antineutrophil cytoplasmic antibody associated vasculitis may promote thromboinflammation and the thrombophilic state associated with the disease.
Kambas K, Chrysanthopoulou A, Vassilopoulos D, Apostolidou E, Skendros P, Girod A, Arelaki S, Froudarakis M, Nakopoulou L, Giatromanolaki A, Sidiropoulos P, Koffa M, Boumpas DT, Ritis K, Mitroulis I. Kambas K, et al. Among authors: skendros p. Ann Rheum Dis. 2014 Oct;73(10):1854-63. doi: 10.1136/annrheumdis-2013-203430. Epub 2013 Jul 19. Ann Rheum Dis. 2014. PMID: 23873874
Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction.
Stakos DA, Kambas K, Konstantinidis T, Mitroulis I, Apostolidou E, Arelaki S, Tsironidou V, Giatromanolaki A, Skendros P, Konstantinides S, Ritis K. Stakos DA, et al. Among authors: skendros p. Eur Heart J. 2015 Jun 7;36(22):1405-14. doi: 10.1093/eurheartj/ehv007. Epub 2015 Feb 7. Eur Heart J. 2015. PMID: 25660055 Free PMC article.
72 results