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The Non-Fibrillating N-Terminal of α-Synuclein Binds and Co-Fibrillates with Heparin.
Biomolecules. 2020 Aug 16;10(8):1192. doi: 10.3390/biom10081192.
Biomolecules. 2020.
PMID: 32824376
Free PMC article.
Monoclonal Antibodies Follow Distinct Aggregation Pathways During Production-Relevant Acidic Incubation and Neutralization.
Skamris T, Tian X, Thorolfsson M, Karkov HS, Rasmussen HB, Langkilde AE, Vestergaard B.
Skamris T, et al.
Pharm Res. 2016 Mar;33(3):716-28. doi: 10.1007/s11095-015-1821-0. Epub 2015 Nov 12.
Pharm Res. 2016.
PMID: 26563206
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Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation.
Lobbens ES, Breydo L, Skamris T, Vestergaard B, Jäger AK, Jorgensen L, Uversky V, van de Weert M.
Lobbens ES, et al. Among authors: skamris t.
Biochim Biophys Acta. 2016 Sep;1864(9):1160-1169. doi: 10.1016/j.bbapap.2016.06.009. Epub 2016 Jun 21.
Biochim Biophys Acta. 2016.
PMID: 27353564
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Formation of covalent di-tyrosine dimers in recombinant α-synuclein.
van Maarschalkerweerd A, Pedersen MN, Peterson H, Nilsson M, Nguyen T, Skamris T, Rand K, Vetri V, Langkilde AE, Vestergaard B.
van Maarschalkerweerd A, et al. Among authors: skamris t.
Intrinsically Disord Proteins. 2015 Oct 19;3(1):e1071302. doi: 10.1080/21690707.2015.1071302. eCollection 2015.
Intrinsically Disord Proteins. 2015.
PMID: 28232892
Free PMC article.
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Early Stage Alpha-Synuclein Amyloid Fibrils are Reservoirs of Membrane-Binding Species.
Skamris T, Marasini C, Madsen KL, Foderà V, Vestergaard B.
Skamris T, et al.
Sci Rep. 2019 Feb 11;9(1):1733. doi: 10.1038/s41598-018-38271-2.
Sci Rep. 2019.
PMID: 30741994
Free PMC article.
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Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies.
Dos Santos AB, Skaanning LK, Thaneshwaran S, Mikkelsen E, Romero-Leguizamón CR, Skamris T, Kristensen MP, Langkilde AE, Kohlmeier KA.
Dos Santos AB, et al. Among authors: skamris t.
Cell Mol Life Sci. 2022 Jul 26;79(8):450. doi: 10.1007/s00018-022-04467-z.
Cell Mol Life Sci. 2022.
PMID: 35882665
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Identifying Biological and Biophysical Features of Different Maturation States of α-Synuclein Amyloid Fibrils.
Skamris T, Vestergaard B, Madsen KL, Langkilde AE, Foderà V.
Skamris T, et al.
Methods Mol Biol. 2023;2551:321-344. doi: 10.1007/978-1-0716-2597-2_22.
Methods Mol Biol. 2023.
PMID: 36310213
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