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An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers.
Mezheyeuski A, Backman M, Mattsson J, Martín-Bernabé A, Larsson C, Hrynchyk I, Hammarström K, Ström S, Ekström J, Mauchanski S, Khelashvili S, Lindberg A, Agnarsdóttir M, Edqvist PH, Huvila J, Segersten U, Malmström PU, Botling J, Nodin B, Hedner C, Borg D, Brändstedt J, Sartor H, Leandersson K, Glimelius B, Portyanko A, Ponten F, Jirström K, Micke P, Sjöblom T. Mezheyeuski A, et al. Among authors: sjoblom t. EBioMedicine. 2023 Feb;88:104452. doi: 10.1016/j.ebiom.2023.104452. Epub 2023 Jan 30. EBioMedicine. 2023. PMID: 36724681 Free PMC article.
The genomic landscapes of human breast and colorectal cancers.
Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, Nikolsky Y, Karchin R, Wilson PA, Kaminker JS, Zhang Z, Croshaw R, Willis J, Dawson D, Shipitsin M, Willson JK, Sukumar S, Polyak K, Park BH, Pethiyagoda CL, Pant PV, Ballinger DG, Sparks AB, Hartigan J, Smith DR, Suh E, Papadopoulos N, Buckhaults P, Markowitz SD, Parmigiani G, Kinzler KW, Velculescu VE, Vogelstein B. Wood LD, et al. Among authors: sjoblom t. Science. 2007 Nov 16;318(5853):1108-13. doi: 10.1126/science.1145720. Epub 2007 Oct 11. Science. 2007. PMID: 17932254
Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes.
Willard MD, Lajiness ME, Wulur IH, Feng B, Swearingen ML, Uhlik MT, Kinzler KW, Velculescu VE, Sjöblom T, Markowitz SD, Powell SM, Vogelstein B, Barber TD. Willard MD, et al. Among authors: sjoblom t. Mol Cancer Res. 2012 Jun;10(6):739-49. doi: 10.1158/1541-7786.MCR-11-0483. Epub 2012 Apr 19. Mol Cancer Res. 2012. PMID: 22516348 Free PMC article.
Large-scale identification of novel transcripts in the human genome.
Peters BA, St Croix B, Sjöblom T, Cummins JM, Silliman N, Ptak J, Saha S, Kinzler KW, Hatzis C, Velculescu VE. Peters BA, et al. Among authors: sjoblom t. Genome Res. 2007 Mar;17(3):287-92. doi: 10.1101/gr.5486607. Epub 2007 Jan 31. Genome Res. 2007. PMID: 17267814 Free PMC article.
116 results