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BCL-xL inhibition potentiates cancer therapies by redirecting the outcome of p53 activation from senescence to apoptosis.
Bharti V, Watkins R, Kumar A, Shattuck-Brandt RL, Mossing A, Mittra A, Shen C, Tsung A, Davies AE, Hanel W, Reneau JC, Chung C, Sizemore GM, Richmond A, Weiss VL, Vilgelm AE. Bharti V, et al. Among authors: sizemore gm. Cell Rep. 2022 Dec 20;41(12):111826. doi: 10.1016/j.celrep.2022.111826. Cell Rep. 2022. PMID: 36543138 Free PMC article.
Synthetic Lethality of PARP Inhibition and Ionizing Radiation is p53-dependent.
Sizemore ST, Mohammad R, Sizemore GM, Nowsheen S, Yu H, Ostrowski MC, Chakravarti A, Xia F. Sizemore ST, et al. Among authors: sizemore gm. Mol Cancer Res. 2018 Jul;16(7):1092-1102. doi: 10.1158/1541-7786.MCR-18-0106. Epub 2018 Mar 28. Mol Cancer Res. 2018. PMID: 29592899 Free PMC article.
CD200 is overexpressed in the pancreatic tumor microenvironment and predictive of overall survival.
Wedig J, Jasani S, Mukherjee D, Lathrop H, Matreja P, Pfau T, D'Alesio L, Guenther A, Fenn L, Kaiser M, Torok MA, McGue J, Sizemore GM, Noonan AM, Dillhoff ME, Blaser BW, Frankel TL, Culp S, Hart PA, Cruz-Monserrate Z, Mace TA. Wedig J, et al. Among authors: sizemore gm. Cancer Immunol Immunother. 2024 Apr 15;73(6):96. doi: 10.1007/s00262-024-03678-6. Cancer Immunol Immunother. 2024. PMID: 38619621 Free PMC article.
PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance.
Russell L, Swanner J, Jaime-Ramirez AC, Wang Y, Sprague A, Banasavadi-Siddegowda Y, Yoo JY, Sizemore GM, Kladney R, Zhang J, Lehman NL, Ostrowski MC, Hong B, Caligiuri M, Yu J, Kaur B. Russell L, et al. Among authors: sizemore gm. Nat Commun. 2018 Nov 27;9(1):5006. doi: 10.1038/s41467-018-07344-1. Nat Commun. 2018. PMID: 30479334 Free PMC article.
Ablation of the Brca1-Palb2 Interaction Phenocopies Fanconi Anemia in Mice.
Park D, Bergin SM, Jones D, Ru P, Koivisto CS, Jeon YJ, Sizemore GM, Kladney RD, Hadjis A, Shakya R, Ludwig T. Park D, et al. Among authors: sizemore gm. Cancer Res. 2020 Oct 1;80(19):4172-4184. doi: 10.1158/0008-5472.CAN-20-0486. Epub 2020 Jul 30. Cancer Res. 2020. PMID: 32732220
The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer.
Thies KA, Cole MW, Schafer RE, Spehar JM, Richardson DS, Steck SA, Das M, Lian AW, Ray A, Shakya R, Knoblaugh SE, Timmers CD, Ostrowski MC, Chakravarti A, Sizemore GM, Sizemore ST. Thies KA, et al. Among authors: sizemore gm. Breast Cancer Res. 2021 Jun 12;23(1):65. doi: 10.1186/s13058-021-01438-3. Breast Cancer Res. 2021. PMID: 34118960 Free PMC article.
43 results