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Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT6 receptor with anti-aggregation properties against amyloid-beta and tau.
Wichur T, Pasieka A, Godyń J, Panek D, Góral I, Latacz G, Honkisz-Orzechowska E, Bucki A, Siwek A, Głuch-Lutwin M, Knez D, Brazzolotto X, Gobec S, Kołaczkowski M, Sabate R, Malawska B, Więckowska A. Wichur T, et al. Among authors: siwek a. Eur J Med Chem. 2021 Dec 5;225:113783. doi: 10.1016/j.ejmech.2021.113783. Epub 2021 Aug 19. Eur J Med Chem. 2021. PMID: 34461507 Free article.
Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT(1A) activity. part 3.
Herold F, Chodkowski A, Izbicki Ł, Turło J, Dawidowski M, Kleps J, Nowak G, Stachowicz K, Dybała M, Siwek A, Mazurek AP, Mazurek A, Pluciński F. Herold F, et al. Among authors: siwek a. Eur J Med Chem. 2011 Jan;46(1):142-9. doi: 10.1016/j.ejmech.2010.10.026. Epub 2010 Oct 29. Eur J Med Chem. 2011. PMID: 21093118
Antidepressant and antipsychotic activity of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole targeting serotonin 5-HT₁A/5-HT₂A/5-HT₇ and dopamine D₂/D₃ receptors.
Zajdel P, Marciniec K, Maślankiewicz A, Grychowska K, Satała G, Duszyńska B, Lenda T, Siwek A, Nowak G, Partyka A, Wróbel D, Jastrzębska-Więsek M, Bojarski AJ, Wesołowska A, Pawłowski M. Zajdel P, et al. Among authors: siwek a. Eur J Med Chem. 2013 Feb;60:42-50. doi: 10.1016/j.ejmech.2012.11.042. Epub 2012 Dec 5. Eur J Med Chem. 2013. PMID: 23279866
Synthesis and biological evaluation of novel pyrrolidine-2,5-dione derivatives as potential antidepressant agents. Part 1.
Wróbel MZ, Chodkowski A, Herold F, Gomółka A, Kleps J, Mazurek AP, Pluciński F, Mazurek A, Nowak G, Siwek A, Stachowicz K, Sławińska A, Wolak M, Szewczyk B, Satała G, Bojarski AJ, Turło J. Wróbel MZ, et al. Among authors: siwek a. Eur J Med Chem. 2013 May;63:484-500. doi: 10.1016/j.ejmech.2013.02.033. Epub 2013 Mar 5. Eur J Med Chem. 2013. PMID: 23524160
190 results