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Anti-Alzheimer's multitarget-directed ligands with serotonin 5-HT6 antagonist, butyrylcholinesterase inhibitory, and antioxidant activity.
Marcinkowska M, Bucki A, Panek D, Siwek A, Fajkis N, Bednarski M, Zygmunt M, Godyń J, Del Rio Valdivieso A, Kotańska M, Kołaczkowski M, Więckowska A. Marcinkowska M, et al. Among authors: siwek a. Arch Pharm (Weinheim). 2019 Jul;352(7):e1900041. doi: 10.1002/ardp.201900041. Epub 2019 Jun 4. Arch Pharm (Weinheim). 2019. PMID: 31162703
Synthesis and adrenolytic activity of new propanolamines.
Groszek G, Bajek A, Bis A, Nowak-Król A, Bednarski M, Siwek A, Filipek B. Groszek G, et al. Among authors: siwek a. Molecules. 2010 May 28;15(6):3887-904. doi: 10.3390/molecules15063887. Molecules. 2010. PMID: 20657415 Free PMC article.
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
Kołaczkowski M, Marcinkowska M, Bucki A, Pawłowski M, Mitka K, Jaśkowska J, Kowalski P, Kazek G, Siwek A, Wasik A, Wesołowska A, Mierzejewski P, Bienkowski P. Kołaczkowski M, et al. Among authors: siwek a. J Med Chem. 2014 Jun 12;57(11):4543-57. doi: 10.1021/jm401895u. Epub 2014 May 23. J Med Chem. 2014. PMID: 24805037
Pharmacological evaluation of the anxiolytic-like effects of EMD 386088, a partial 5-HT6 receptor agonist, in the rat elevated plus-maze and Vogel conflict tests.
Jastrzębska-Więsek M, Siwek A, Partyka A, Kubacka M, Mogilski S, Wasik A, Kołaczkowski M, Wesołowska A. Jastrzębska-Więsek M, et al. Among authors: siwek a. Neuropharmacology. 2014 Oct;85:253-62. doi: 10.1016/j.neuropharm.2014.05.036. Epub 2014 Jun 4. Neuropharmacology. 2014. PMID: 24905144
190 results