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Structure-Activity Relationship of Novel Second-Generation Synthetic Cathinones: Mechanism of Action, Locomotion, Reward, and Immediate-Early Genes.
Nadal-Gratacós N, Alberto-Silva AS, Rodríguez-Soler M, Urquizu E, Espinosa-Velasco M, Jäntsch K, Holy M, Batllori X, Berzosa X, Pubill D, Camarasa J, Sitte HH, Escubedo E, López-Arnau R. Nadal-Gratacós N, et al. Among authors: sitte hh. Front Pharmacol. 2021 Oct 26;12:749429. doi: 10.3389/fphar.2021.749429. eCollection 2021. Front Pharmacol. 2021. PMID: 34764870 Free PMC article.
The N terminus of monoamine transporters is a lever required for the action of amphetamines.
Sucic S, Dallinger S, Zdrazil B, Weissensteiner R, Jørgensen TN, Holy M, Kudlacek O, Seidel S, Cha JH, Gether U, Newman AH, Ecker GF, Freissmuth M, Sitte HH. Sucic S, et al. Among authors: sitte hh. J Biol Chem. 2010 Apr 2;285(14):10924-38. doi: 10.1074/jbc.M109.083154. Epub 2010 Jan 29. J Biol Chem. 2010. PMID: 20118234 Free PMC article.
Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate.
Buchmayer F, Schicker K, Steinkellner T, Geier P, Stübiger G, Hamilton PJ, Jurik A, Stockner T, Yang JW, Montgomery T, Holy M, Hofmaier T, Kudlacek O, Matthies HJ, Ecker GF, Bochkov V, Galli A, Boehm S, Sitte HH. Buchmayer F, et al. Among authors: sitte hh. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11642-7. doi: 10.1073/pnas.1220552110. Epub 2013 Jun 24. Proc Natl Acad Sci U S A. 2013. PMID: 23798435 Free PMC article.
199 results