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Alzheimer's disease: genetic studies and transgenic models.
Price DL, Tanzi RE, Borchelt DR, Sisodia SS. Price DL, et al. Among authors: sisodia ss. Annu Rev Genet. 1998;32:461-93. doi: 10.1146/annurev.genet.32.1.461. Annu Rev Genet. 1998. PMID: 9928488 Review.
Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta.
Vetrivel KS, Zhang X, Meckler X, Cheng H, Lee S, Gong P, Lopes KO, Chen Y, Iwata N, Yin KJ, Lee JM, Parent AT, Saido TC, Li YM, Sisodia SS, Thinakaran G. Vetrivel KS, et al. Among authors: sisodia ss. J Biol Chem. 2008 Jul 11;283(28):19489-98. doi: 10.1074/jbc.M801037200. Epub 2008 May 1. J Biol Chem. 2008. PMID: 18456655 Free PMC article.
Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease.
Kounnas MZ, Danks AM, Cheng S, Tyree C, Ackerman E, Zhang X, Ahn K, Nguyen P, Comer D, Mao L, Yu C, Pleynet D, Digregorio PJ, Velicelebi G, Stauderman KA, Comer WT, Mobley WC, Li YM, Sisodia SS, Tanzi RE, Wagner SL. Kounnas MZ, et al. Among authors: sisodia ss. Neuron. 2010 Sep 9;67(5):769-80. doi: 10.1016/j.neuron.2010.08.018. Neuron. 2010. PMID: 20826309 Free PMC article.
Activation and intrinsic gamma-secretase activity of presenilin 1.
Ahn K, Shelton CC, Tian Y, Zhang X, Gilchrist ML, Sisodia SS, Li YM. Ahn K, et al. Among authors: sisodia ss. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21435-40. doi: 10.1073/pnas.1013246107. Epub 2010 Nov 29. Proc Natl Acad Sci U S A. 2010. PMID: 21115843 Free PMC article.
230 results