Siskind LJ - Search Results

1

Neutral ceramidase deficiency protects against cisplatin-induced acute kidney injury.

Sears SM, Dupre TV, Shah PP, Davis DL, Doll MA, Sharp CN, Vega AA, Megyesi J, Beverly LJ, Snider AJ, Obeid LM, Hannun YA, Siskind LJ. Sears SM, et al. Among authors: siskind lj. J Lipid Res. 2022 Mar;63(3):100179. doi: 10.1016/j.jlr.2022.100179. Epub 2022 Feb 10. J Lipid Res. 2022. PMID: 35151662 Free PMC article.

2

The BCL-2 protein BAK is required for long-chain ceramide generation during apoptosis.

Siskind LJ, Mullen TD, Romero Rosales K, Clarke CJ, Hernandez-Corbacho MJ, Edinger AL, Obeid LM. Siskind LJ, et al. J Biol Chem. 2010 Apr 16;285(16):11818-26. doi: 10.1074/jbc.M109.078121. Epub 2010 Feb 18. J Biol Chem. 2010. PMID: 20172858 Free PMC article.

3

Accumulation of long-chain glycosphingolipids during aging is prevented by caloric restriction.

Hernández-Corbacho MJ, Jenkins RW, Clarke CJ, Hannun YA, Obeid LM, Snider AJ, Siskind LJ. Hernández-Corbacho MJ, et al. Among authors: siskind lj. PLoS One. 2011;6(6):e20411. doi: 10.1371/journal.pone.0020411. Epub 2011 Jun 8. PLoS One. 2011. PMID: 21687659 Free PMC article.

4

Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis.

Chipuk JE, McStay GP, Bharti A, Kuwana T, Clarke CJ, Siskind LJ, Obeid LM, Green DR. Chipuk JE, et al. Among authors: siskind lj. Cell. 2012 Mar 2;148(5):988-1000. doi: 10.1016/j.cell.2012.01.038. Cell. 2012. PMID: 22385963 Free PMC article.

5

Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2-like proteins.

Casson L, Howell L, Mathews LA, Ferrer M, Southall N, Guha R, Keller JM, Thomas C, Siskind LJ, Beverly LJ. Casson L, et al. Among authors: siskind lj. PLoS One. 2013;8(1):e54525. doi: 10.1371/journal.pone.0054525. Epub 2013 Jan 16. PLoS One. 2013. PMID: 23342165 Free PMC article.

6

BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins.

Beverly LJ, Howell LA, Hernandez-Corbacho M, Casson L, Chipuk JE, Siskind LJ. Beverly LJ, et al. Among authors: siskind lj. Biochem J. 2013 May 15;452(1):111-9. doi: 10.1042/BJ20130147. Biochem J. 2013. PMID: 23480852 Free PMC article.

7

Defining a role for acid sphingomyelinase in the p38/interleukin-6 pathway.

Perry DM, Newcomb B, Adada M, Wu BX, Roddy P, Kitatani K, Siskind L, Obeid LM, Hannun YA. Perry DM, et al. J Biol Chem. 2014 Aug 8;289(32):22401-12. doi: 10.1074/jbc.M114.589648. Epub 2014 Jun 20. J Biol Chem. 2014. PMID: 24951586 Free PMC article.

8

Glucose availability and glycolytic metabolism dictate glycosphingolipid levels.

Stathem M, Marimuthu S, O'Neal J, Rathmell JC, Chesney JA, Beverly LJ, Siskind LJ. Stathem M, et al. Among authors: siskind lj. J Cell Biochem. 2015 Jan;116(1):67-80. doi: 10.1002/jcb.24943. J Cell Biochem. 2015. PMID: 25145677 Free PMC article.

9

Renal glycosphingolipid metabolism is dysfunctional in lupus nephritis.

Nowling TK, Mather AR, Thiyagarajan T, Hernández-Corbacho MJ, Powers TW, Jones EE, Snider AJ, Oates JC, Drake RR, Siskind LJ. Nowling TK, et al. Among authors: siskind lj. J Am Soc Nephrol. 2015 Jun;26(6):1402-13. doi: 10.1681/ASN.2014050508. Epub 2014 Sep 30. J Am Soc Nephrol. 2015. PMID: 25270066 Free PMC article.

10

Sphingolipids and mitochondrial apoptosis.

Patwardhan GA, Beverly LJ, Siskind LJ. Patwardhan GA, et al. Among authors: siskind lj. J Bioenerg Biomembr. 2016 Apr;48(2):153-68. doi: 10.1007/s10863-015-9602-3. J Bioenerg Biomembr. 2016. PMID: 25620271 Free PMC article. Review.

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