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Impact of natural selection on global patterns of genetic variation and association with clinical phenotypes at genes involved in SARS-CoV-2 infection.
Zhang C, Verma A, Feng Y, Melo MCR, McQuillan M, Hansen M, Lucas A, Park J, Ranciaro A, Thompson S, Rubel MA, Campbell MC, Beggs W, Hirbo J, Wata Mpoloka S, George Mokone G; Regeneron Genetic Center; Nyambo T, Wolde Meskel D, Belay G, Fokunang C, Njamnshi AK, Omar SA, Williams SM, Rader DJ, Ritchie MD, de la Fuente-Nunez C, Sirugo G, Tishkoff SA. Zhang C, et al. Among authors: sirugo g. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2123000119. doi: 10.1073/pnas.2123000119. Epub 2022 May 17. Proc Natl Acad Sci U S A. 2022. PMID: 35580180 Free PMC article.
The Missing Diversity in Human Genetic Studies.
Sirugo G, Williams SM, Tishkoff SA. Sirugo G, et al. Cell. 2019 Mar 21;177(1):26-31. doi: 10.1016/j.cell.2019.02.048. Cell. 2019. PMID: 30901543 Free PMC article.
Embracing African Genetic Diversity.
Williams SM, Sirugo G, Tishkoff SA. Williams SM, et al. Among authors: sirugo g. Med. 2021 Jan 15;2(1):19-20. doi: 10.1016/j.medj.2020.12.019. Med. 2021. PMID: 35590130 Free article.
Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease.
Horowitz JE, Kosmicki JA, Damask A, Sharma D, Roberts GHL, Justice AE, Banerjee N, Coignet MV, Yadav A, Leader JB, Marcketta A, Park DS, Lanche R, Maxwell E, Knight SC, Bai X, Guturu H, Sun D, Baltzell A, Kury FSP, Backman JD, Girshick AR, O'Dushlaine C, McCurdy SR, Partha R, Mansfield AJ, Turissini DA, Li AH, Zhang M, Mbatchou J, Watanabe K, Gurski L, McCarthy SE, Kang HM, Dobbyn L, Stahl E, Verma A, Sirugo G; Regeneron Genetics Center; Ritchie MD, Jones M, Balasubramanian S, Siminovitch K, Salerno WJ, Shuldiner AR, Rader DJ, Mirshahi T, Locke AE, Marchini J, Overton JD, Carey DJ, Habegger L, Cantor MN, Rand KA, Hong EL, Reid JG, Ball CA, Baras A, Abecasis GR, Ferreira MAR. Horowitz JE, et al. Among authors: sirugo g. Nat Genet. 2022 Apr;54(4):382-392. doi: 10.1038/s41588-021-01006-7. Epub 2022 Mar 3. Nat Genet. 2022. PMID: 35241825 Free PMC article.
The Plight of Muntaser Ibrahim.
Sirugo G, Williams SM, Tishkoff SA, Cordell HJ, Marchini J, Barsh GS, Copenhaver GP. Sirugo G, et al. PLoS Genet. 2019 Mar 25;15(3):e1008100. doi: 10.1371/journal.pgen.1008100. eCollection 2019 Mar. PLoS Genet. 2019. PMID: 30908486 Free PMC article. No abstract available.
Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals.
Kosmicki JA, Horowitz JE, Banerjee N, Lanche R, Marcketta A, Maxwell E, Bai X, Sun D, Backman JD, Sharma D, Kury FSP, Kang HM, O'Dushlaine C, Yadav A, Mansfield AJ, Li AH, Watanabe K, Gurski L, McCarthy SE, Locke AE, Khalid S, O'Keeffe S, Mbatchou J, Chazara O, Huang Y, Kvikstad E, O'Neill A, Nioi P, Parker MM, Petrovski S, Runz H, Szustakowski JD, Wang Q, Wong E, Cordova-Palomera A, Smith EN, Szalma S, Zheng X, Esmaeeli S, Davis JW, Lai YP, Chen X, Justice AE, Leader JB, Mirshahi T, Carey DJ, Verma A, Sirugo G, Ritchie MD, Rader DJ, Povysil G, Goldstein DB, Kiryluk K, Pairo-Castineira E, Rawlik K, Pasko D, Walker S, Meynert A, Kousathanas A, Moutsianas L, Tenesa A, Caulfield M, Scott R, Wilson JF, Baillie JK, Butler-Laporte G, Nakanishi T, Lathrop M, Richards JB; Regeneron Genetics Center; UKB Exome Sequencing Consortium; Jones M, Balasubramanian S, Salerno W, Shuldiner AR, Marchini J, Overton JD, Habegger L, Cantor MN, Reid JG, Baras A, Abecasis GR, Ferreira MAR. Kosmicki JA, et al. Among authors: sirugo g. Am J Hum Genet. 2021 Jul 1;108(7):1350-1355. doi: 10.1016/j.ajhg.2021.05.017. Epub 2021 Jun 3. Am J Hum Genet. 2021. PMID: 34115965 Free PMC article.
The Missing Diversity in Human Genetic Studies.
Sirugo G, Williams SM, Tishkoff SA. Sirugo G, et al. Cell. 2019 May 2;177(4):1080. doi: 10.1016/j.cell.2019.04.032. Cell. 2019. PMID: 31051100 Free article. No abstract available.
A Locus at 5q33.3 Confers Resistance to Tuberculosis in Highly Susceptible Individuals.
Sobota RS, Stein CM, Kodaman N, Scheinfeldt LB, Maro I, Wieland-Alter W, Igo RP Jr, Magohe A, Malone LL, Chervenak K, Hall NB, Modongo C, Zetola N, Matee M, Joloba M, Froment A, Nyambo TB, Moore JH, Scott WK, Lahey T, Boom WH, von Reyn CF, Tishkoff SA, Sirugo G, Williams SM. Sobota RS, et al. Among authors: sirugo g. Am J Hum Genet. 2016 Mar 3;98(3):514-524. doi: 10.1016/j.ajhg.2016.01.015. Am J Hum Genet. 2016. PMID: 26942285 Free PMC article.
Evaluating the strength of genetic results: Risks and responsibilities.
Barsh GS, Cooper GM, Copenhaver GP, Sirugo G, Tang H, Williams SM. Barsh GS, et al. Among authors: sirugo g. PLoS Genet. 2019 Oct 11;15(10):e1008437. doi: 10.1371/journal.pgen.1008437. eCollection 2019 Oct. PLoS Genet. 2019. PMID: 31603891 Free PMC article. No abstract available.
135 results