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Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.
Villa A, Klein B, Janssen B, Pedragosa J, Pepe G, Zinnhardt B, Vugts DJ, Gelosa P, Sironi L, Beaino W, Damont A, Dollé F, Jego B, Winkeler A, Ory D, Solin O, Vercouillie J, Funke U, Laner-Plamberger S, Blomster LV, Christophersen P, Vegeto E, Aigner L, Jacobs A, Planas AM, Maggi A, Windhorst AD. Villa A, et al. Among authors: sironi l. Theranostics. 2018 Oct 27;8(19):5400-5418. doi: 10.7150/thno.25572. eCollection 2018. Theranostics. 2018. PMID: 30555554 Free PMC article.
Pentoxifylline prevents spontaneous brain ischemia in stroke-prone rats.
Banfi C, Sironi L, De Simoni G, Gelosa P, Barcella S, Perego C, Gianazza E, Guerrini U, Tremoli E, Mussoni L. Banfi C, et al. Among authors: sironi l. J Pharmacol Exp Ther. 2004 Sep;310(3):890-5. doi: 10.1124/jpet.104.067090. Epub 2004 Jun 16. J Pharmacol Exp Ther. 2004. PMID: 15201342 Free article.
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor.
Ciana P, Fumagalli M, Trincavelli ML, Verderio C, Rosa P, Lecca D, Ferrario S, Parravicini C, Capra V, Gelosa P, Guerrini U, Belcredito S, Cimino M, Sironi L, Tremoli E, Rovati GE, Martini C, Abbracchio MP. Ciana P, et al. Among authors: sironi l. EMBO J. 2006 Oct 4;25(19):4615-27. doi: 10.1038/sj.emboj.7601341. Epub 2006 Sep 21. EMBO J. 2006. PMID: 16990797 Free PMC article.
The interleukin-8 (IL-8/CXCL8) receptor inhibitor reparixin improves neurological deficits and reduces long-term inflammation in permanent and transient cerebral ischemia in rats.
Villa P, Triulzi S, Cavalieri B, Di Bitondo R, Bertini R, Barbera S, Bigini P, Mennini T, Gelosa P, Tremoli E, Sironi L, Ghezzi P. Villa P, et al. Among authors: sironi l. Mol Med. 2007 Mar-Apr;13(3-4):125-33. doi: 10.2119/2007–00008.Villa. Mol Med. 2007. PMID: 17592546 Free PMC article.
The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair.
Lecca D, Trincavelli ML, Gelosa P, Sironi L, Ciana P, Fumagalli M, Villa G, Verderio C, Grumelli C, Guerrini U, Tremoli E, Rosa P, Cuboni S, Martini C, Buffo A, Cimino M, Abbracchio MP. Lecca D, et al. Among authors: sironi l. PLoS One. 2008;3(10):e3579. doi: 10.1371/journal.pone.0003579. Epub 2008 Oct 31. PLoS One. 2008. PMID: 18974869 Free PMC article.
192 results