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Cellular Senescence Is Immunogenic and Promotes Antitumor Immunity.
Marin I, Boix O, Garcia-Garijo A, Sirois I, Caballe A, Zarzuela E, Ruano I, Attolini CS, Prats N, López-Domínguez JA, Kovatcheva M, Garralda E, Muñoz J, Caron E, Abad M, Gros A, Pietrocola F, Serrano M. Marin I, et al. Among authors: sirois i. Cancer Discov. 2023 Feb 6;13(2):410-431. doi: 10.1158/2159-8290.CD-22-0523. Cancer Discov. 2023. PMID: 36302218 Free PMC article.
Understanding the constitutive presentation of MHC class I immunopeptidomes in primary tissues.
Kubiniok P, Marcu A, Bichmann L, Kuchenbecker L, Schuster H, Hamelin DJ, Duquette JD, Kovalchik KA, Wessling L, Kohlbacher O, Rammensee HG, Neidert MC, Sirois I, Caron E. Kubiniok P, et al. Among authors: sirois i. iScience. 2022 Jan 18;25(2):103768. doi: 10.1016/j.isci.2022.103768. eCollection 2022 Feb 18. iScience. 2022. PMID: 35141507 Free PMC article.
HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin.
Biondini M, Kiepas A, El-Houjeiri L, Annis MG, Hsu BE, Fortier AM, Morin G, Martina JA, Sirois I, Aguilar-Mahecha A, Gruosso T, McGuirk S, Rose AAN, Tokat UM, Johnson RM, Sahin O, Bareke E, St-Pierre J, Park M, Basik M, Majewski J, Puertollano R, Pause A, Huang S, Keler T, Siegel PM. Biondini M, et al. Among authors: sirois i. Oncogene. 2022 Mar;41(12):1701-1717. doi: 10.1038/s41388-022-02206-z. Epub 2022 Feb 2. Oncogene. 2022. PMID: 35110681
MhcVizPipe: A Quality Control Software for Rapid Assessment of Small- to Large-Scale Immunopeptidome Datasets.
Kovalchik KA, Ma Q, Wessling L, Saab F, Duquette JD, Kubiniok P, Hamelin DJ, Faridi P, Li C, Purcell AW, Jang A, Paramithiotis E, Tognetti M, Reiter L, Bruderer R, Lanoix J, Bonneil É, Courcelles M, Thibault P, Caron E, Sirois I. Kovalchik KA, et al. Among authors: sirois i. Mol Cell Proteomics. 2022 Jan;21(1):100178. doi: 10.1016/j.mcpro.2021.100178. Epub 2021 Nov 17. Mol Cell Proteomics. 2022. PMID: 34798331 Free PMC article.
The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA-supertype-dependent manner.
Hamelin DJ, Fournelle D, Grenier JC, Schockaert J, Kovalchik KA, Kubiniok P, Mostefai F, Duquette JD, Saab F, Sirois I, Smith MA, Pattijn S, Soudeyns H, Decaluwe H, Hussin J, Caron E. Hamelin DJ, et al. Among authors: sirois i. Cell Syst. 2022 Feb 16;13(2):143-157.e3. doi: 10.1016/j.cels.2021.09.013. Epub 2021 Oct 6. Cell Syst. 2022. PMID: 34637888 Free PMC article.
The Human Immunopeptidome Project: A Roadmap to Predict and Treat Immune Diseases.
Vizcaíno JA, Kubiniok P, Kovalchik KA, Ma Q, Duquette JD, Mongrain I, Deutsch EW, Peters B, Sette A, Sirois I, Caron E. Vizcaíno JA, et al. Among authors: sirois i. Mol Cell Proteomics. 2020 Jan;19(1):31-49. doi: 10.1074/mcp.R119.001743. Epub 2019 Nov 19. Mol Cell Proteomics. 2020. PMID: 31744855 Free PMC article.
26 results