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NEDD4 degrades TUSC2 to promote glioblastoma progression.
Rimkus TK, Arrigo AB, Zhu D, Carpenter RL, Sirkisoon S, Doheny D, Regua AT, Wong GL, Manore S, Wagner C, Lin HK, Jin G, Ruiz J, Chan M, Debinski W, Lo HW. Rimkus TK, et al. Among authors: sirkisoon s. Cancer Lett. 2022 Apr 10;531:124-135. doi: 10.1016/j.canlet.2022.01.029. Epub 2022 Feb 12. Cancer Lett. 2022. PMID: 35167936 Free PMC article.
EGFR and HER2 signaling in breast cancer brain metastasis.
Sirkisoon SR, Carpenter RL, Rimkus T, Miller L, Metheny-Barlow L, Lo HW. Sirkisoon SR, et al. Front Biosci (Elite Ed). 2016 Jan 1;8(2):245-63. doi: 10.2741/E765. Front Biosci (Elite Ed). 2016. PMID: 26709660 Free PMC article.
Combined inhibition of AKT and HSF1 suppresses breast cancer stem cells and tumor growth.
Carpenter RL, Sirkisoon S, Zhu D, Rimkus T, Harrison A, Anderson A, Paw I, Qasem S, Xing F, Liu Y, Chan M, Metheny-Barlow L, Pasche BC, Debinski W, Watabe K, Lo HW. Carpenter RL, et al. Among authors: sirkisoon s. Oncotarget. 2017 May 22;8(43):73947-73963. doi: 10.18632/oncotarget.18166. eCollection 2017 Sep 26. Oncotarget. 2017. PMID: 29088759 Free PMC article.
TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment.
Sirkisoon SR, Carpenter RL, Rimkus T, Doheny D, Zhu D, Aguayo NR, Xing F, Chan M, Ruiz J, Metheny-Barlow LJ, Strowd R, Lin J, Regua AT, Arrigo A, Anguelov M, Pasche B, Debinski W, Watabe K, Lo HW. Sirkisoon SR, et al. Oncogene. 2020 Jan;39(1):64-78. doi: 10.1038/s41388-019-0959-3. Epub 2019 Aug 28. Oncogene. 2020. PMID: 31462709 Free PMC article.
Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis.
Doheny D, Sirkisoon S, Carpenter RL, Aguayo NR, Regua AT, Anguelov M, Manore SG, Arrigo A, Jalboush SA, Wong GL, Yu Y, Wagner CJ, Chan M, Ruiz J, Thomas A, Strowd R, Lin J, Lo HW. Doheny D, et al. Among authors: sirkisoon s. Oncogene. 2020 Oct;39(42):6589-6605. doi: 10.1038/s41388-020-01454-1. Epub 2020 Sep 14. Oncogene. 2020. PMID: 32929154 Free PMC article.
17 results