Siqueira-Neto JL - Search Results

1

Current and Future Chemotherapy for Chagas Disease.

Gaspar L, Moraes CB, Freitas-Junior LH, Ferrari S, Costantino L, Costi MP, Coron RP, Smith TK, Siqueira-Neto JL, McKerrow JH, Cordeiro-da-Silva A. Gaspar L, et al. Curr Med Chem. 2015;22(37):4293-312. doi: 10.2174/0929867322666151015120804. Curr Med Chem. 2015. PMID: 26477622 Free article. Review.

2

Automated nuclear analysis of Leishmania major telomeric clusters reveals changes in their organization during the parasite's life cycle.

Dossin Fde M, Dufour A, Dusch E, Siqueira-Neto JL, Moraes CB, Yang GS, Cano MI, Genovesio A, Freitas-Junior LH. Dossin Fde M, et al. PLoS One. 2008 Jun 11;3(6):e2313. doi: 10.1371/journal.pone.0002313. PLoS One. 2008. PMID: 18545650 Free PMC article.

3

Antileishmanial high-throughput drug screening reveals drug candidates with new scaffolds.

Siqueira-Neto JL, Song OR, Oh H, Sohn JH, Yang G, Nam J, Jang J, Cechetto J, Lee CB, Moon S, Genovesio A, Chatelain E, Christophe T, Freitas-Junior LH. Siqueira-Neto JL, et al. PLoS Negl Trop Dis. 2010 May 4;4(5):e675. doi: 10.1371/journal.pntd.0000675. PLoS Negl Trop Dis. 2010. PMID: 20454559 Free PMC article.

4

An image-based high-content screening assay for compounds targeting intracellular Leishmania donovani amastigotes in human macrophages.

Siqueira-Neto JL, Moon S, Jang J, Yang G, Lee C, Moon HK, Chatelain E, Genovesio A, Cechetto J, Freitas-Junior LH. Siqueira-Neto JL, et al. PLoS Negl Trop Dis. 2012;6(6):e1671. doi: 10.1371/journal.pntd.0001671. Epub 2012 Jun 12. PLoS Negl Trop Dis. 2012. PMID: 22720099 Free PMC article.

5

An image-based algorithm for precise and accurate high throughput assessment of drug activity against the human parasite Trypanosoma cruzi.

Moon S, Siqueira-Neto JL, Moraes CB, Yang G, Kang M, Freitas-Junior LH, Hansen MA. Moon S, et al. PLoS One. 2014 Feb 4;9(2):e87188. doi: 10.1371/journal.pone.0087188. eCollection 2014. PLoS One. 2014. PMID: 24503652 Free PMC article.

6

Visceral leishmaniasis treatment: What do we have, what do we need and how to deliver it?

Freitas-Junior LH, Chatelain E, Kim HA, Siqueira-Neto JL. Freitas-Junior LH, et al. Int J Parasitol Drugs Drug Resist. 2012 Jan 28;2:11-9. doi: 10.1016/j.ijpddr.2012.01.003. eCollection 2012 Dec. Int J Parasitol Drugs Drug Resist. 2012. PMID: 24533267 Free PMC article. Review.

7

Diversity-oriented synthesis yields a new drug lead for treatment of chagas disease.

Dandapani S, Germain AR, Jewett I, le Quement S, Marie JC, Muncipinto G, Duvall JR, Carmody LC, Perez JR, Engel JC, Gut J, Kellar D, Siqueira-Neto JL, McKerrow JH, Kaiser M, Rodriguez A, Palmer MA, Foley M, Schreiber SL, Munoz B. Dandapani S, et al. ACS Med Chem Lett. 2013 Dec 29;5(2):149-53. doi: 10.1021/ml400403u. eCollection 2014 Feb 13. ACS Med Chem Lett. 2013. PMID: 24900788 Free PMC article.

8

Synthesis and biological evaluation of 2,3-dihydroimidazo[1,2-a]benzimidazole derivatives against Leishmania donovani and Trypanosoma cruzi.

Oh S, Kim S, Kong S, Yang G, Lee N, Han D, Goo J, Siqueira-Neto JL, Freitas-Junior LH, Song R. Oh S, et al. Eur J Med Chem. 2014 Sep 12;84:395-403. doi: 10.1016/j.ejmech.2014.07.038. Epub 2014 Jul 11. Eur J Med Chem. 2014. PMID: 25036797

9

4-Aminopyridyl-based CYP51 inhibitors as anti-Trypanosoma cruzi drug leads with improved pharmacokinetic profile and in vivo potency.

Calvet CM, Vieira DF, Choi JY, Kellar D, Cameron MD, Siqueira-Neto JL, Gut J, Johnston JB, Lin L, Khan S, McKerrow JH, Roush WR, Podust LM. Calvet CM, et al. J Med Chem. 2014 Aug 28;57(16):6989-7005. doi: 10.1021/jm500448u. Epub 2014 Aug 19. J Med Chem. 2014. PMID: 25101801 Free PMC article.

10

Lead identification to clinical candidate selection: drugs for Chagas disease.

Neitz RJ, Chen S, Supek F, Yeh V, Kellar D, Gut J, Bryant C, Gallardo-Godoy A, Molteni V, Roach SL, Khare S, Stinson M, Chatterjee AK, Robertson S, Renslo AR, Arkin M, Glynne R, McKerrow J, Siqueira-Neto JL. Neitz RJ, et al. J Biomol Screen. 2015 Jan;20(1):101-11. doi: 10.1177/1087057114553103. Epub 2014 Oct 3. J Biomol Screen. 2015. PMID: 25281737

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