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Exercise-induced irisin secretion is independent of age or fitness level and increased irisin may directly modulate muscle metabolism through AMPK activation.
Huh JY, Mougios V, Kabasakalis A, Fatouros I, Siopi A, Douroudos II, Filippaios A, Panagiotou G, Park KH, Mantzoros CS. Huh JY, et al. Among authors: siopi a. J Clin Endocrinol Metab. 2014 Nov;99(11):E2154-61. doi: 10.1210/jc.2014-1437. Epub 2014 Aug 13. J Clin Endocrinol Metab. 2014. PMID: 25119310
Circulating irisin in healthy, young individuals: day-night rhythm, effects of food intake and exercise, and associations with gender, physical activity, diet, and body composition.
Anastasilakis AD, Polyzos SA, Saridakis ZG, Kynigopoulos G, Skouvaklidou EC, Molyvas D, Vasiloglou MF, Apostolou A, Karagiozoglou-Lampoudi T, Siopi A, Mougios V, Chatzistavridis P, Panagiotou G, Filippaios A, Delaroudis S, Mantzoros CS. Anastasilakis AD, et al. Among authors: siopi a. J Clin Endocrinol Metab. 2014 Sep;99(9):3247-55. doi: 10.1210/jc.2014-1367. Epub 2014 Jun 10. J Clin Endocrinol Metab. 2014. PMID: 24915120
Exercise in the management of obesity.
Petridou A, Siopi A, Mougios V. Petridou A, et al. Among authors: siopi a. Metabolism. 2019 Mar;92:163-169. doi: 10.1016/j.metabol.2018.10.009. Epub 2018 Oct 29. Metabolism. 2019. PMID: 30385379 Review.
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