Sinnis P - Search Results

1

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness.

Mok S, Yeo T, Hong D, Shears MJ, Ross LS, Ward KE, Dhingra SK, Kanai M, Bridgford JL, Tripathi AK, Mlambo G, Burkhard AY, Ansbro MR, Fairhurst KJ, Gil-Iturbe E, Park H, Rozenberg FD, Kim J, Mancia F, Fairhurst RM, Quick M, Uhlemann AC, Sinnis P, Fidock DA. Mok S, et al. Among authors: sinnis p. Sci Adv. 2023 Nov 10;9(45):eadi2364. doi: 10.1126/sciadv.adi2364. Epub 2023 Nov 8. Sci Adv. 2023. PMID: 37939186 Free PMC article.

2

Transgenic Plasmodium berghei sporozoites expressing beta-galactosidase for quantification of sporozoite transmission.

Engelmann S, Sinnis P, Matuschewski K. Engelmann S, et al. Among authors: sinnis p. Mol Biochem Parasitol. 2006 Mar;146(1):30-7. doi: 10.1016/j.molbiopara.2005.10.015. Epub 2005 Nov 15. Mol Biochem Parasitol. 2006. PMID: 16316690 Free PMC article.

3

The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host.

Coppi A, Natarajan R, Pradel G, Bennett BL, James ER, Roggero MA, Corradin G, Persson C, Tewari R, Sinnis P. Coppi A, et al. Among authors: sinnis p. J Exp Med. 2011 Feb 14;208(2):341-56. doi: 10.1084/jem.20101488. Epub 2011 Jan 24. J Exp Med. 2011. PMID: 21262960 Free PMC article.

4

Proteasome inhibitors block development of Plasmodium spp.

Gantt SM, Myung JM, Briones MR, Li WD, Corey EJ, Omura S, Nussenzweig V, Sinnis P. Gantt SM, et al. Among authors: sinnis p. Antimicrob Agents Chemother. 1998 Oct;42(10):2731-8. doi: 10.1128/AAC.42.10.2731. Antimicrob Agents Chemother. 1998. PMID: 9756786 Free PMC article.

5

The skin stage of malaria infection: biology and relevance to the malaria vaccine effort.

Sinnis P, Zavala F. Sinnis P, et al. Future Microbiol. 2008 Jun;3(3):275-8. doi: 10.2217/17460913.3.3.275. Future Microbiol. 2008. PMID: 18505393 Review.

6

The binding of the circumsporozoite protein to cell surface heparan sulfate proteoglycans is required for plasmodium sporozoite attachment to target cells.

Pinzon-Ortiz C, Friedman J, Esko J, Sinnis P. Pinzon-Ortiz C, et al. Among authors: sinnis p. J Biol Chem. 2001 Jul 20;276(29):26784-91. doi: 10.1074/jbc.M104038200. Epub 2001 May 14. J Biol Chem. 2001. PMID: 11352923 Free PMC article.

7

Cell adhesion to a motif shared by the malaria circumsporozoite protein and thrombospondin is mediated by its glycosaminoglycan-binding region and not by CSVTCG.

Gantt SM, Clavijo P, Bai X, Esko JD, Sinnis P. Gantt SM, et al. Among authors: sinnis p. J Biol Chem. 1997 Aug 1;272(31):19205-13. doi: 10.1074/jbc.272.31.19205. J Biol Chem. 1997. PMID: 9235912 Free PMC article.

8

Apolipoprotein E-derived antimicrobial peptide analogues with altered membrane affinity and increased potency and breadth of activity.

Kelly BA, Neil SJ, McKnight A, Santos JM, Sinnis P, Jack ER, Middleton DA, Dobson CB. Kelly BA, et al. Among authors: sinnis p. FEBS J. 2007 Sep;274(17):4511-25. doi: 10.1111/j.1742-4658.2007.05981.x. Epub 2007 Aug 6. FEBS J. 2007. PMID: 17681018 Free article.

9

Remnant lipoproteins inhibit malaria sporozoite invasion of hepatocytes.

Sinnis P, Willnow TE, Briones MR, Herz J, Nussenzweig V. Sinnis P, et al. J Exp Med. 1996 Sep 1;184(3):945-54. doi: 10.1084/jem.184.3.945. J Exp Med. 1996. PMID: 9064354 Free PMC article.

10

Extrahepatic exoerythrocytic forms of rodent malaria parasites at the site of inoculation: clearance after immunization, susceptibility to primaquine, and contribution to blood-stage infection.

Voza T, Miller JL, Kappe SH, Sinnis P. Voza T, et al. Among authors: sinnis p. Infect Immun. 2012 Jun;80(6):2158-64. doi: 10.1128/IAI.00246-12. Epub 2012 Mar 19. Infect Immun. 2012. PMID: 22431651 Free PMC article.

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