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Sildenafil Potentiates a cGMP-Dependent Pathway to Promote Melanoma Growth.
Dhayade S, Kaesler S, Sinnberg T, Dobrowinski H, Peters S, Naumann U, Liu H, Hunger RE, Thunemann M, Biedermann T, Schittek B, Simon HU, Feil S, Feil R. Dhayade S, et al. Among authors: sinnberg t. Cell Rep. 2016 Mar 22;14(11):2599-610. doi: 10.1016/j.celrep.2016.02.028. Epub 2016 Mar 10. Cell Rep. 2016. PMID: 26971999 Free article.
Dermcidin-derived peptides show a different mode of action than the cathelicidin LL-37 against Staphylococcus aureus.
Senyürek I, Paulmann M, Sinnberg T, Kalbacher H, Deeg M, Gutsmann T, Hermes M, Kohler T, Götz F, Wolz C, Peschel A, Schittek B. Senyürek I, et al. Among authors: sinnberg t. Antimicrob Agents Chemother. 2009 Jun;53(6):2499-509. doi: 10.1128/AAC.01679-08. Epub 2009 Apr 13. Antimicrob Agents Chemother. 2009. PMID: 19364862 Free PMC article.
The farnesyl transferase inhibitor lonafarnib inhibits mTOR signaling and enforces sorafenib-induced apoptosis in melanoma cells.
Niessner H, Beck D, Sinnberg T, Lasithiotakis K, Maczey E, Gogel J, Venturelli S, Berger A, Mauthe M, Toulany M, Flaherty K, Schaller M, Schadendorf D, Proikas-Cezanne T, Schittek B, Garbe C, Kulms D, Meier F. Niessner H, et al. Among authors: sinnberg t. J Invest Dermatol. 2011 Feb;131(2):468-79. doi: 10.1038/jid.2010.297. Epub 2010 Oct 14. J Invest Dermatol. 2011. PMID: 20944654 Free article.
Vemurafenib potently induces endoplasmic reticulum stress-mediated apoptosis in BRAFV600E melanoma cells.
Beck D, Niessner H, Smalley KS, Flaherty K, Paraiso KH, Busch C, Sinnberg T, Vasseur S, Iovanna JL, Drießen S, Stork B, Wesselborg S, Schaller M, Biedermann T, Bauer J, Lasithiotakis K, Weide B, Eberle J, Schittek B, Schadendorf D, Garbe C, Kulms D, Meier F. Beck D, et al. Among authors: sinnberg t. Sci Signal. 2013 Jan 29;6(260):ra7. doi: 10.1126/scisignal.2003057. Sci Signal. 2013. PMID: 23362240 Free PMC article. Clinical Trial.
85 results