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The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice.
Fan Y, Støving RK, Berreira Ibraim S, Hyötyläinen T, Thirion F, Arora T, Lyu L, Stankevic E, Hansen TH, Déchelotte P, Sinioja T, Ragnarsdottir O, Pons N, Galleron N, Quinquis B, Levenez F, Roume H, Falony G, Vieira-Silva S, Raes J, Clausen L, Telléus GK, Bäckhed F, Oresic M, Ehrlich SD, Pedersen O. Fan Y, et al. Among authors: sinioja t. Nat Microbiol. 2023 May;8(5):787-802. doi: 10.1038/s41564-023-01355-5. Epub 2023 Apr 17. Nat Microbiol. 2023. PMID: 37069399 Free PMC article.
Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model.
Lützhøft DO, Sinioja T, Christoffersen BØ, Jakobsen RR, Geng D, Ahmad HFB, Straarup EM, Pedersen KM, Kot W, Pedersen HD, Cirera S, Hyötyläinen T, Nielsen DS, Hansen AK. Lützhøft DO, et al. Among authors: sinioja t. BMC Microbiol. 2022 Dec 1;22(1):287. doi: 10.1186/s12866-022-02704-w. BMC Microbiol. 2022. PMID: 36456963 Free PMC article.
Quantitative modeling of human liver reveals dysregulation of glycosphingolipid pathways in nonalcoholic fatty liver disease.
Sen P, Govaere O, Sinioja T, McGlinchey A, Geng D, Ratziu V, Bugianesi E, Schattenberg JM, Vidal-Puig A, Allison M, Cockell S, Daly AK, Hyötyläinen T, Anstee QM, Orešič M. Sen P, et al. Among authors: sinioja t. iScience. 2022 Aug 15;25(9):104949. doi: 10.1016/j.isci.2022.104949. eCollection 2022 Sep 16. iScience. 2022. PMID: 36065182 Free PMC article.
Serum metabolome associated with severity of acute traumatic brain injury.
Thomas I, Dickens AM, Posti JP, Czeiter E, Duberg D, Sinioja T, Kråkström M, Retel Helmrich IRA, Wang KKW, Maas AIR, Steyerberg EW, Menon DK, Tenovuo O, Hyötyläinen T, Büki A, Orešič M; CENTER-TBI Participants and Investigators. Thomas I, et al. Among authors: sinioja t. Nat Commun. 2022 May 10;13(1):2545. doi: 10.1038/s41467-022-30227-5. Nat Commun. 2022. PMID: 35538079 Free PMC article.
Prenatal exposure to perfluoroalkyl substances modulates neonatal serum phospholipids, increasing risk of type 1 diabetes.
McGlinchey A, Sinioja T, Lamichhane S, Sen P, Bodin J, Siljander H, Dickens AM, Geng D, Carlsson C, Duberg D, Ilonen J, Virtanen SM, Dirven H, Berntsen HF, Zimmer K, Nygaard UC, Orešič M, Knip M, Hyötyläinen T. McGlinchey A, et al. Among authors: sinioja t. Environ Int. 2020 Oct;143:105935. doi: 10.1016/j.envint.2020.105935. Epub 2020 Jul 4. Environ Int. 2020. PMID: 32634666 Free article.