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Odontoblast TRPC5 channels signal cold pain in teeth.
Bernal L, Sotelo-Hitschfeld P, König C, Sinica V, Wyatt A, Winter Z, Hein A, Touska F, Reinhardt S, Tragl A, Kusuda R, Wartenberg P, Sclaroff A, Pfeifer JD, Ectors F, Dahl A, Freichel M, Vlachova V, Brauchi S, Roza C, Boehm U, Clapham DE, Lennerz JK, Zimmermann K. Bernal L, et al. Among authors: sinica v. Sci Adv. 2021 Mar 26;7(13):eabf5567. doi: 10.1126/sciadv.abf5567. Print 2021 Mar. Sci Adv. 2021. PMID: 33771873 Free PMC article.
Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nadezhdin KD, Neuberger A, Trofimov YA, Krylov NA, Sinica V, Kupko N, Vlachova V, Zakharian E, Efremov RG, Sobolevsky AI. Nadezhdin KD, et al. Among authors: sinica v. Nat Struct Mol Biol. 2021 Jul;28(7):564-572. doi: 10.1038/s41594-021-00615-4. Epub 2021 Jul 8. Nat Struct Mol Biol. 2021. PMID: 34239124 Free PMC article.