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Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity.
Kalafati L, Kourtzelis I, Schulte-Schrepping J, Li X, Hatzioannou A, Grinenko T, Hagag E, Sinha A, Has C, Dietz S, de Jesus Domingues AM, Nati M, Sormendi S, Neuwirth A, Chatzigeorgiou A, Ziogas A, Lesche M, Dahl A, Henry I, Subramanian P, Wielockx B, Murray P, Mirtschink P, Chung KJ, Schultze JL, Netea MG, Hajishengallis G, Verginis P, Mitroulis I, Chavakis T. Kalafati L, et al. Among authors: sinha a. Cell. 2020 Oct 29;183(3):771-785.e12. doi: 10.1016/j.cell.2020.09.058. Cell. 2020. PMID: 33125892 Free PMC article.
HIF1α is a direct regulator of steroidogenesis in the adrenal gland.
Watts D, Stein J, Meneses A, Bechmann N, Neuwirth A, Kaden D, Krüger A, Sinha A, Alexaki VI, Luis Gustavo Perez-Rivas, Kircher S, Martinez A, Theodoropoulou M, Eisenhofer G, Peitzsch M, El-Armouche A, Chavakis T, Wielockx B. Watts D, et al. Among authors: sinha a. Cell Mol Life Sci. 2021 Apr;78(7):3577-3590. doi: 10.1007/s00018-020-03750-1. Epub 2021 Jan 19. Cell Mol Life Sci. 2021. PMID: 33464382 Free PMC article.
HIF2α is a direct regulator of neutrophil motility.
Sormendi S, Deygas M, Sinha A, Bernard M, Krüger A, Kourtzelis I, Le Lay G, Sáez PJ, Gerlach M, Franke K, Meneses A, Kräter M, Palladini A, Guck J, Coskun Ü, Chavakis T, Vargas P, Wielockx B. Sormendi S, et al. Among authors: sinha a. Blood. 2021 Jun 17;137(24):3416-3427. doi: 10.1182/blood.2020007505. Blood. 2021. PMID: 33619535 Free article.
The RNA binding protein human antigen R is a gatekeeper of liver homeostasis.
Subramanian P, Gargani S, Palladini A, Chatzimike M, Grzybek M, Peitzsch M, Papanastasiou AD, Pyrina I, Ntafis V, Gercken B, Lesche M, Petzold A, Sinha A, Nati M, Thangapandi VR, Kourtzelis I, Andreadou M, Witt A, Dahl A, Burkhardt R, Haase R, Domingues AMJ, Henry I, Zamboni N, Mirtschink P, Chung KJ, Hampe J, Coskun Ü, Kontoyiannis DL, Chavakis T. Subramanian P, et al. Among authors: sinha a. Hepatology. 2022 Apr;75(4):881-897. doi: 10.1002/hep.32153. Epub 2021 Dec 5. Hepatology. 2022. PMID: 34519101 Free article.
Succinate mediates inflammation-induced adrenocortical dysfunction.
Mateska I, Witt A, Hagag E, Sinha A, Yilmaz C, Thanou E, Sun N, Kolliniati O, Patschin M, Abdelmegeed H, Henneicke H, Kanczkowski W, Wielockx B, Tsatsanis C, Dahl A, Walch AK, Li KW, Peitzsch M, Chavakis T, Alexaki VI. Mateska I, et al. Among authors: sinha a. Elife. 2023 Jul 14;12:e83064. doi: 10.7554/eLife.83064. Elife. 2023. PMID: 37449973 Free PMC article.
Fatty acid desaturase 2 determines the lipidomic landscape and steroidogenic function of the adrenal gland.
Witt A, Mateska I, Palladini A, Sinha A, Wölk M, Harauma A, Bechmann N, Pamporaki C, Dahl A, Rothe M, Kopaliani I, Adolf C, Riester A, Wielockx B, Bornstein SR, Kroiss M, Peitzsch M, Moriguchi T, Fedorova M, Grzybek M, Chavakis T, Mirtschink P, Alexaki VI. Witt A, et al. Among authors: sinha a. Sci Adv. 2023 Jul 21;9(29):eadf6710. doi: 10.1126/sciadv.adf6710. Epub 2023 Jul 21. Sci Adv. 2023. PMID: 37478183 Free PMC article.
CD38 promotes hematopoietic stem cell dormancy.
Ibneeva L, Singh SP, Sinha A, Eski SE, Wehner R, Rupp L, Kovtun I, Pérez-Valencia JA, Gerbaulet A, Reinhardt S, Wobus M, von Bonin M, Sancho J, Lund F, Dahl A, Schmitz M, Bornhäuser M, Chavakis T, Wielockx B, Grinenko T. Ibneeva L, et al. Among authors: sinha a. PLoS Biol. 2024 Feb 29;22(2):e3002517. doi: 10.1371/journal.pbio.3002517. eCollection 2024 Feb. PLoS Biol. 2024. PMID: 38422172 Free PMC article.
Dickkopf1 fuels inflammatory cytokine responses.
Jaschke NP, Pählig S, Sinha A, Adolph TE, Colunga ML, Hofmann M, Wang A, Thiele S, Schwärzler J, Kleymann A, Gentzel M, Tilg H, Wielockx B, Hofbauer LC, Rauner M, Göbel A, Rachner TD. Jaschke NP, et al. Among authors: sinha a. Commun Biol. 2022 Dec 20;5(1):1391. doi: 10.1038/s42003-022-04368-8. Commun Biol. 2022. PMID: 36539532 Free PMC article.
Circulating Dickkopf1 Parallels Metabolic Adaptations and Predicts Disease Trajectories in Patients With COVID-19.
Jaschke NP, Funk AM, Jonas S, Riffel RM, Sinha A, Wang A, Pählig S, Hofmann M, Altmann H, Von Bonin S, Koch T, Spieth P, Tausche K, Akgün K, Rauner M, Kronstein-Wiedemann R, Odendahl M, Tonn T, Göbel A, Hofbauer LC, Rachner TD. Jaschke NP, et al. Among authors: sinha a. J Clin Endocrinol Metab. 2022 Nov 25;107(12):3370-3377. doi: 10.1210/clinem/dgac514. J Clin Endocrinol Metab. 2022. PMID: 36071553 Free PMC article.
4,128 results