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Transforming growth factor-β1 and SMAD signalling pathway in the small airways of smokers and patients with COPD: potential role in driving fibrotic type-2 epithelial mesenchymal transition.
Brake SJ, Lu W, Chia C, Haug G, Larby J, Hardikar A, Singhera GK, Hackett TL, Eapen MS, Sohal SS. Brake SJ, et al. Among authors: singhera gk. Front Immunol. 2023 Jun 26;14:1216506. doi: 10.3389/fimmu.2023.1216506. eCollection 2023. Front Immunol. 2023. PMID: 37435075 Free PMC article.
Formation of a stable mimic of ambient particulate matter containing viable infectious respiratory syncytial virus and its dry-deposition directly onto cell cultures.
Cruz-Sanchez TM, Haddrell AE, Hackett TL, Singhera GK, Marchant D, Lekivetz R, Meredith A, Horne D, Knight DA, van Eeden SF, Bai TR, Hegele RG, Dorscheid DR, Agnes GR. Cruz-Sanchez TM, et al. Among authors: singhera gk. Anal Chem. 2013 Jan 15;85(2):898-906. doi: 10.1021/ac302174y. Epub 2012 Dec 19. Anal Chem. 2013. PMID: 23205519
Dysregulation of endocytic machinery and ACE2 in small airways of smokers and COPD patients can augment their susceptibility to SARS-CoV-2 (COVID-19) infections.
Eapen MS, Lu W, Hackett TL, Singhera GK, Thompson IE, McAlinden KD, Hardikar A, Weber HC, Haug G, Wark PAB, Chia C, Sohal SS. Eapen MS, et al. Among authors: singhera gk. Am J Physiol Lung Cell Mol Physiol. 2021 Jan 1;320(1):L158-L163. doi: 10.1152/ajplung.00437.2020. Epub 2020 Nov 11. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33174446 Free PMC article.
FAM13A as potential therapeutic target in modulating TGF-β-induced airway tissue remodeling in COPD.
Tam A, Leclair P, Li LV, Yang CX, Li X, Witzigmann D, Kulkarni JA, Hackett TL, Dorscheid DR, Singhera GK, Hogg JC, Cullis PR, Sin DD, Lim CJ. Tam A, et al. Among authors: singhera gk. Am J Physiol Lung Cell Mol Physiol. 2021 Aug 1;321(2):L377-L391. doi: 10.1152/ajplung.00477.2020. Epub 2021 Jun 9. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34105356 Free article.
Increased myofibroblasts in the small airways, and relationship to remodelling and functional changes in smokers and COPD patients: potential role of epithelial-mesenchymal transition.
Eapen MS, Lu W, Hackett TL, Singhera GK, Mahmood MQ, Hardikar A, Ward C, Walters EH, Sohal SS. Eapen MS, et al. Among authors: singhera gk. ERJ Open Res. 2021 Jun 7;7(2):00876-2020. doi: 10.1183/23120541.00876-2020. eCollection 2021 Apr. ERJ Open Res. 2021. PMID: 34109247 Free PMC article.
41 results