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Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Peptidase Serine 2 (TMPRSS2), and Furin Expression Increases in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lymphangioleiomyomatosis (LAM): Implications for SARS-CoV-2 (COVID-19) Infections.
Lu W, Eapen MS, Singhera GK, Markos J, Haug G, Chia C, Larby J, Brake SJ, Westall GP, Jaffar J, Kalidhindi RSR, Fonseka N, Sathish V, Hackett TL, Sohal SS. Lu W, et al. Among authors: singhera gk. J Clin Med. 2022 Jan 31;11(3):777. doi: 10.3390/jcm11030777. J Clin Med. 2022. PMID: 35160229 Free PMC article.
Dysregulation of endocytic machinery and ACE2 in small airways of smokers and COPD patients can augment their susceptibility to SARS-CoV-2 (COVID-19) infections.
Eapen MS, Lu W, Hackett TL, Singhera GK, Thompson IE, McAlinden KD, Hardikar A, Weber HC, Haug G, Wark PAB, Chia C, Sohal SS. Eapen MS, et al. Among authors: singhera gk. Am J Physiol Lung Cell Mol Physiol. 2021 Jan 1;320(1):L158-L163. doi: 10.1152/ajplung.00437.2020. Epub 2020 Nov 11. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33174446 Free PMC article.
Increased myofibroblasts in the small airways, and relationship to remodelling and functional changes in smokers and COPD patients: potential role of epithelial-mesenchymal transition.
Eapen MS, Lu W, Hackett TL, Singhera GK, Mahmood MQ, Hardikar A, Ward C, Walters EH, Sohal SS. Eapen MS, et al. Among authors: singhera gk. ERJ Open Res. 2021 Jun 7;7(2):00876-2020. doi: 10.1183/23120541.00876-2020. eCollection 2021 Apr. ERJ Open Res. 2021. PMID: 34109247 Free PMC article.
SARS-CoV-2 (COVID-19) Adhesion Site Protein Upregulation in Small Airways, Type 2 Pneumocytes, and Alveolar Macrophages of Smokers and COPD - Possible Implications for Interstitial Fibrosis.
Brake SJ, Eapen MS, McAlinden KD, Markos J, Haug G, Larby J, Chia C, Hardikar A, Singhera GK, Hackett TL, Lu W, Sohal SS. Brake SJ, et al. Among authors: singhera gk. Int J Chron Obstruct Pulmon Dis. 2022 Jan 11;17:101-115. doi: 10.2147/COPD.S329783. eCollection 2022. Int J Chron Obstruct Pulmon Dis. 2022. PMID: 35046647 Free PMC article.
Vascular remodelling in idiopathic pulmonary fibrosis patients and its detrimental effect on lung physiology: potential role of endothelial-to-mesenchymal transition.
Gaikwad AV, Lu W, Dey S, Bhattarai P, Chia C, Larby J, Haug G, Myers S, Jaffar J, Westall G, Singhera GK, Hackett TL, Markos J, Eapen MS, Sohal SS. Gaikwad AV, et al. Among authors: singhera gk. ERJ Open Res. 2022 Mar 21;8(1):00571-2021. doi: 10.1183/23120541.00571-2021. eCollection 2022 Jan. ERJ Open Res. 2022. PMID: 35350273 Free PMC article.
Endothelial-to-mesenchymal transition: a precursor to pulmonary arterial remodelling in patients with idiopathic pulmonary fibrosis.
Gaikwad AV, Lu W, Dey S, Bhattarai P, Haug G, Larby J, Chia C, Jaffar J, Westall G, Singhera GK, Hackett TL, Eapen MS, Sohal SS. Gaikwad AV, et al. Among authors: singhera gk. ERJ Open Res. 2023 Apr 17;9(2):00487-2022. doi: 10.1183/23120541.00487-2022. eCollection 2023 Mar. ERJ Open Res. 2023. PMID: 37077555 Free PMC article.
Transforming growth factor-β1 and SMAD signalling pathway in the small airways of smokers and patients with COPD: potential role in driving fibrotic type-2 epithelial mesenchymal transition.
Brake SJ, Lu W, Chia C, Haug G, Larby J, Hardikar A, Singhera GK, Hackett TL, Eapen MS, Sohal SS. Brake SJ, et al. Among authors: singhera gk. Front Immunol. 2023 Jun 26;14:1216506. doi: 10.3389/fimmu.2023.1216506. eCollection 2023. Front Immunol. 2023. PMID: 37435075 Free PMC article.
41 results