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Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells.
Singh N, Frey NV, Engels B, Barrett DM, Shestova O, Ravikumar P, Cummins KD, Lee YG, Pajarillo R, Chun I, Shyu A, Highfill SL, Price A, Zhao L, Peng L, Granda B, Ramones M, Lu XM, Christian DA, Perazzelli J, Lacey SF, Roy NH, Burkhardt JK, Colomb F, Damra M, Abdel-Mohsen M, Liu T, Liu D, Standley DM, Young RM, Brogdon JL, Grupp SA, June CH, Maude SL, Gill S, Ruella M. Singh N, et al. Nat Med. 2021 May;27(5):842-850. doi: 10.1038/s41591-021-01326-5. Epub 2021 Apr 22. Nat Med. 2021. PMID: 33888899 Free PMC article. Clinical Trial.
Chimeric antigen receptor therapy for cancer.
Barrett DM, Singh N, Porter DL, Grupp SA, June CH. Barrett DM, et al. Among authors: singh n. Annu Rev Med. 2014;65:333-47. doi: 10.1146/annurev-med-060512-150254. Epub 2013 Nov 20. Annu Rev Med. 2014. PMID: 24274181 Free PMC article. Review.
Roadblocks to success for RNA CARs in solid tumors.
Singh N, Barrett DM, Grupp SA. Singh N, et al. Oncoimmunology. 2015 Jan 7;3(12):e962974. doi: 10.4161/21624011.2014.962974. eCollection 2014 Dec. Oncoimmunology. 2015. PMID: 25964863 Free PMC article.
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