Singh J - Search Results

1

Polypharmacological repurposing approach identifies approved drugs as potential inhibitors of Mycobacterium tuberculosis.

Singh J, Quadir N, Vashishtha S, Chakraborty A, Alam A, Kundu B, Ahmad U, Sundar D, Ehtesham NZ, Hasnain SE. Singh J, et al. Biochem J. 2023 Jul 26;480(14):1079-1096. doi: 10.1042/BCJ20230143. Biochem J. 2023. PMID: 37306466

2

L-Asparaginase as a new molecular target against leishmaniasis: insights into the mechanism of action and structure-based inhibitor design.

Singh J, Srivastava A, Jha P, Sinha KK, Kundu B. Singh J, et al. Mol Biosyst. 2015 Jul;11(7):1887-96. doi: 10.1039/c5mb00251f. Mol Biosyst. 2015. PMID: 25893895

3

Modulation of prion polymerization and toxicity by rationally designed peptidomimetics.

Srivastava A, Sharma S, Sadanandan S, Gupta S, Singh J, Gupta S, Haridas V, Kundu B. Srivastava A, et al. Among authors: singh j. Biochem J. 2017 Jan 1;474(1):123-147. doi: 10.1042/BCJ20160737. Epub 2016 Nov 1. Biochem J. 2017. PMID: 27803245

4

Polyphenols in combination with β-cyclodextrin can inhibit and disaggregate α-synuclein amyloids under cell mimicking conditions: A promising therapeutic alternative.

Gautam S, Karmakar S, Batra R, Sharma P, Pradhan P, Singh J, Kundu B, Chowdhury PK. Gautam S, et al. Among authors: singh j. Biochim Biophys Acta Proteins Proteom. 2017 May;1865(5):589-603. doi: 10.1016/j.bbapap.2017.02.014. Epub 2017 Feb 24. Biochim Biophys Acta Proteins Proteom. 2017. PMID: 28238838

5

Arjunolic acid, a peroxisome proliferator-activated receptor α agonist, regresses cardiac fibrosis by inhibiting non-canonical TGF-β signaling.

Bansal T, Chatterjee E, Singh J, Ray A, Kundu B, Thankamani V, Sengupta S, Sarkar S. Bansal T, et al. Among authors: singh j. J Biol Chem. 2017 Oct 6;292(40):16440-16462. doi: 10.1074/jbc.M117.788299. Epub 2017 Aug 18. J Biol Chem. 2017. PMID: 28821620 Free PMC article.

6

L-Asparaginase of Leishmania donovani: Metabolic target and its role in Amphotericin B resistance.

Singh J, Khan MI, Singh Yadav SP, Srivastava A, Sinha KK, Ashish, Das P, Kundu B. Singh J, et al. Among authors: singh yadav sp. Int J Parasitol Drugs Drug Resist. 2017 Dec;7(3):337-349. doi: 10.1016/j.ijpddr.2017.09.003. Epub 2017 Sep 28. Int J Parasitol Drugs Drug Resist. 2017. PMID: 28988014 Free PMC article.

7

The Gelsolin Pathogenic D187N Mutant Exhibits Altered Conformational Stability and Forms Amyloidogenic Oligomers.

Srivastava A, Singh J, Singh Yadav SP, Arya P, Kalim F, Rose P, Ashish, Kundu B. Srivastava A, et al. Among authors: singh j, singh yadav sp. Biochemistry. 2018 Apr 24;57(16):2359-2372. doi: 10.1021/acs.biochem.8b00039. Epub 2018 Apr 11. Biochemistry. 2018. PMID: 29637772

8

Identification and validation of l-asparaginase as a potential metabolic target against Mycobacterium tuberculosis.

Kataria A, Singh J, Kundu B. Kataria A, et al. Among authors: singh j. J Cell Biochem. 2019 Jan;120(1):143-154. doi: 10.1002/jcb.27169. Epub 2018 Sep 19. J Cell Biochem. 2019. PMID: 30230585

9

Application of a protein domain as chaperone for enhancing biological activity and stability of other proteins.

Jena R, Garg DK, Achary MMV, Singh J, Tomar R, Choudhury L, Bansal R, Kundu B. Jena R, et al. Among authors: singh j. J Biotechnol. 2020 Feb 20;310:68-79. doi: 10.1016/j.jbiotec.2020.01.017. Epub 2020 Jan 31. J Biotechnol. 2020. PMID: 32014561

10

Emerging genetic diversity among clinical isolates of SARS-CoV-2: Lessons for today.

Sheikh JA, Singh J, Singh H, Jamal S, Khubaib M, Kohli S, Dobrindt U, Rahman SA, Ehtesham NZ, Hasnain SE. Sheikh JA, et al. Among authors: singh j, singh h. Infect Genet Evol. 2020 Oct;84:104330. doi: 10.1016/j.meegid.2020.104330. Epub 2020 Apr 24. Infect Genet Evol. 2020. PMID: 32335334 Free PMC article.

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