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Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant Enterococci (VRE) in Vitro and in Vivo.
Parmar A, Lakshminarayanan R, Iyer A, Mayandi V, Leng Goh ET, Lloyd DG, Chalasani MLS, Verma NK, Prior SH, Beuerman RW, Madder A, Taylor EJ, Singh I. Parmar A, et al. Among authors: singh i. J Med Chem. 2018 Mar 8;61(5):2009-2017. doi: 10.1021/acs.jmedchem.7b01634. Epub 2018 Feb 15. J Med Chem. 2018. PMID: 29363971
Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA).
Malkawi R, Iyer A, Parmar A, Lloyd DG, Leng Goh ET, Taylor EJ, Sarmad S, Madder A, Lakshminarayanan R, Singh I. Malkawi R, et al. Among authors: singh i. Pharmaceutics. 2018 Oct 11;10(4):183. doi: 10.3390/pharmaceutics10040183. Pharmaceutics. 2018. PMID: 30314324 Free PMC article.
Development of teixobactin analogues containing hydrophobic, non-proteogenic amino acids that are highly potent against multidrug-resistant bacteria and biofilms.
Parmar A, Lakshminarayanan R, Iyer A, Goh ETL, To TY, Yam JKH, Yang L, Newire E, Robertson MC, Prior SH, Breukink E, Madder A, Singh I. Parmar A, et al. Among authors: singh i. Eur J Med Chem. 2023 Dec 5;261:115853. doi: 10.1016/j.ejmech.2023.115853. Epub 2023 Oct 7. Eur J Med Chem. 2023. PMID: 37857144
2,738 results