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The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca2+ Homeostasis by Targeting a Unique Ion Channel.
Gupta Y, Sharma N, Singh S, Romero JG, Rajendran V, Mogire RM, Kashif M, Beach J, Jeske W, Poonam, Ogutu BR, Kanzok SM, Akala HM, Legac J, Rosenthal PJ, Rademacher DJ, Durvasula R, Singh AP, Rathi B, Kempaiah P. Gupta Y, et al. Among authors: singh ap, singh s. Pharmaceutics. 2022 Jun 28;14(7):1371. doi: 10.3390/pharmaceutics14071371. Pharmaceutics. 2022. PMID: 35890267 Free PMC article.
Fast-Acting Small Molecules Targeting Malarial Aspartyl Proteases, Plasmepsins, Inhibit Malaria Infection at Multiple Life Stages.
Singh S, Rajendran V, He J, Singh AK, Achieng AO, Vandana, Pant A, Nasamu AS, Pandit M, Singh J, Quadiri A, Gupta N, Poonam, Ghosh PC, Singh BK, Narayanan L, Kempaiah P, Chandra R, Dunn BM, Pandey KC, Goldberg DE, Singh AP, Rathi B. Singh S, et al. Among authors: singh ap, singh ak, singh j, singh bk. ACS Infect Dis. 2019 Feb 8;5(2):184-198. doi: 10.1021/acsinfecdis.8b00197. Epub 2019 Jan 2. ACS Infect Dis. 2019. PMID: 30554511
Novel Antiplasmodial Compounds Leveraged with Multistage Potency against the Parasite Plasmodium falciparum: In Vitro and In Vivo Evaluations and Pharmacokinetic Studies.
Sharma N, Kashif M, Singh V, Fontinha D, Mukherjee B, Kumar D, Singh S, Prudencio M, Singh AP, Rathi B. Sharma N, et al. Among authors: singh ap, singh v, singh s. J Med Chem. 2021 Jun 24;64(12):8666-8683. doi: 10.1021/acs.jmedchem.1c00659. Epub 2021 Jun 14. J Med Chem. 2021. PMID: 34124905
Multistage antiplasmodial activity of hydroxyethylamine compounds, in vitro and in vivo evaluations.
Sharma N, Gupta Y, Bansal M, Singh S, Pathak P, Shahbaaz M, Mathur R, Singh J, Kashif M, Grishina M, Potemkin V, Rajendran V, Poonam, Kempaiah P, Singh AP, Rathi B. Sharma N, et al. Among authors: singh ap, singh j, singh s. RSC Adv. 2020 Sep 25;10(58):35516-35530. doi: 10.1039/d0ra03997g. eCollection 2020 Sep 21. RSC Adv. 2020. PMID: 35686031 Free PMC article.
1,212 results