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Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression.
Korhonen EA, Murtomäki A, Jha SK, Anisimov A, Pink A, Zhang Y, Stritt S, Liaqat I, Stanczuk L, Alderfer L, Sun Z, Kapiainen E, Singh A, Sultan I, Lantta A, Leppänen VM, Eklund L, He Y, Augustin HG, Vaahtomeri K, Saharinen P, Mäkinen T, Alitalo K. Korhonen EA, et al. Among authors: singh a. J Clin Invest. 2022 Aug 1;132(15):e155478. doi: 10.1172/JCI155478. J Clin Invest. 2022. PMID: 35763346 Free PMC article.
Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice.
Boutagy NE, Gamez-Mendez A, Fowler JW, Zhang H, Chaube BK, Esplugues E, Kuo A, Lee S, Horikami D, Zhang J, Citrin KM, Singh AK, Coon BG, Lee MY, Suarez Y, Fernandez-Hernando C, Sessa WC. Boutagy NE, et al. Among authors: singh ak. J Clin Invest. 2024 Jan 4;134(4):e170453. doi: 10.1172/JCI170453. J Clin Invest. 2024. PMID: 38175710 Free PMC article.
Lacteal junction zippering protects against diet-induced obesity.
Zhang F, Zarkada G, Han J, Li J, Dubrac A, Ola R, Genet G, Boyé K, Michon P, Künzel SE, Camporez JP, Singh AK, Fong GH, Simons M, Tso P, Fernández-Hernando C, Shulman GI, Sessa WC, Eichmann A. Zhang F, et al. Among authors: singh ak. Science. 2018 Aug 10;361(6402):599-603. doi: 10.1126/science.aap9331. Science. 2018. PMID: 30093598 Free PMC article.
Targeting the vasculature in cardiometabolic disease.
Boutagy NE, Singh AK, Sessa WC. Boutagy NE, et al. J Clin Invest. 2022 Mar 15;132(6):e148556. doi: 10.1172/JCI148556. J Clin Invest. 2022. PMID: 35289308 Free PMC article. Review.
Fibronectin-Integrin α5 Signaling in Vascular Complications of Type 1 Diabetes.
Chen M, Hu R, Cavinato C, Zhuang ZW, Zhang J, Yun S, Fernandez Tussy P, Singh A, Murtada SI, Tanaka K, Liu M, Fernández-Hernando C, Humphrey JD, Schwartz MA. Chen M, et al. Among authors: singh a. Diabetes. 2022 Sep 1;71(9):2020-2033. doi: 10.2337/db21-0958. Diabetes. 2022. PMID: 35771994 Free PMC article.
MicroRNAs and lipid metabolism.
Aryal B, Singh AK, Rotllan N, Price N, Fernández-Hernando C. Aryal B, et al. Curr Opin Lipidol. 2017 Jun;28(3):273-280. doi: 10.1097/MOL.0000000000000420. Curr Opin Lipidol. 2017. PMID: 28333713 Free PMC article. Review.
Desmosterol suppresses macrophage inflammasome activation and protects against vascular inflammation and atherosclerosis.
Zhang X, McDonald JG, Aryal B, Canfrán-Duque A, Goldberg EL, Araldi E, Ding W, Fan Y, Thompson BM, Singh AK, Li Q, Tellides G, Ordovás-Montanes J, García Milian R, Dixit VD, Ikonen E, Suárez Y, Fernández-Hernando C. Zhang X, et al. Among authors: singh ak. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2107682118. doi: 10.1073/pnas.2107682118. Proc Natl Acad Sci U S A. 2021. PMID: 34782454 Free PMC article.
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