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A general method to improve fluorophores for live-cell and single-molecule microscopy.
Grimm JB, English BP, Chen J, Slaughter JP, Zhang Z, Revyakin A, Patel R, Macklin JJ, Normanno D, Singer RH, Lionnet T, Lavis LD. Grimm JB, et al. Among authors: singer rh. Nat Methods. 2015 Mar;12(3):244-50, 3 p following 250. doi: 10.1038/nmeth.3256. Epub 2015 Jan 19. Nat Methods. 2015. PMID: 25599551 Free PMC article.
Imaging transcription in living cells.
Darzacq X, Yao J, Larson DR, Causse SZ, Bosanac L, de Turris V, Ruda VM, Lionnet T, Zenklusen D, Guglielmi B, Tjian R, Singer RH. Darzacq X, et al. Among authors: singer rh. Annu Rev Biophys. 2009;38:173-96. doi: 10.1146/annurev.biophys.050708.133728. Annu Rev Biophys. 2009. PMID: 19416065 Free PMC article. Review.
Transcription, one allele at a time.
Lionnet T, Singer RH. Lionnet T, et al. Among authors: singer rh. Genome Biol. 2010;11(8):129. doi: 10.1186/gb-2010-11-8-129. Epub 2010 Aug 27. Genome Biol. 2010. PMID: 20796323 Free PMC article.
A transgenic mouse for in vivo detection of endogenous labeled mRNA.
Lionnet T, Czaplinski K, Darzacq X, Shav-Tal Y, Wells AL, Chao JA, Park HY, de Turris V, Lopez-Jones M, Singer RH. Lionnet T, et al. Among authors: singer rh. Nat Methods. 2011 Feb;8(2):165-70. doi: 10.1038/nmeth.1551. Epub 2011 Jan 16. Nat Methods. 2011. PMID: 21240280 Free PMC article.
Transcription goes digital.
Lionnet T, Singer RH. Lionnet T, et al. Among authors: singer rh. EMBO Rep. 2012 Apr 2;13(4):313-21. doi: 10.1038/embor.2012.31. EMBO Rep. 2012. PMID: 22410830 Free PMC article. Review.
363 results