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Landiolol and Organ Failure in Patients With Septic Shock: The STRESS-L Randomized Clinical Trial.
Whitehouse T, Hossain A, Perkins GD, Gordon AC, Bion J, Young D, McAuley D, Singer M, Lord J, Gates S, Veenith T, MacCallum NS, Yeung J, Innes R, Welters I, Boota N, Skilton E, Ghuman B, Hill M, Regan SE, Mistry D, Lall R; STRESS-L Collaborators. Whitehouse T, et al. Among authors: singer m. JAMA. 2023 Nov 7;330(17):1641-1652. doi: 10.1001/jama.2023.20134. JAMA. 2023. PMID: 37877587 Free PMC article.
Mitochondrial Dysfunction in Sepsis.
Brealey D, Singer M. Brealey D, et al. Among authors: singer m. Curr Infect Dis Rep. 2003 Oct;5(5):365-371. doi: 10.1007/s11908-003-0015-9. Curr Infect Dis Rep. 2003. PMID: 13678565
Mitochondrial dysfunction in a long-term rodent model of sepsis and organ failure.
Brealey D, Karyampudi S, Jacques TS, Novelli M, Stidwill R, Taylor V, Smolenski RT, Singer M. Brealey D, et al. Among authors: singer m. Am J Physiol Regul Integr Comp Physiol. 2004 Mar;286(3):R491-7. doi: 10.1152/ajpregu.00432.2003. Epub 2003 Nov 6. Am J Physiol Regul Integr Comp Physiol. 2004. PMID: 14604843 Free article.
Mitochondrial dysfunction in patients with severe sepsis: an EPR interrogation of individual respiratory chain components.
Svistunenko DA, Davies N, Brealey D, Singer M, Cooper CE. Svistunenko DA, et al. Among authors: singer m. Biochim Biophys Acta. 2006 Apr;1757(4):262-72. doi: 10.1016/j.bbabio.2006.03.007. Epub 2006 Mar 30. Biochim Biophys Acta. 2006. PMID: 16626626 Free article.
We have previously demonstrated in these same muscle biopsies that biochemical assays of mitochondrial dysfunction correlate with clinical outcomes (D. Brealey, M. Brand, I. Hargreaves, S. Heales, J. Land, R. Smolenski, N.A. Davies, C.E. Cooper, M. Singer, As …
We have previously demonstrated in these same muscle biopsies that biochemical assays of mitochondrial dysfunction correlate with clinical o …
Hyperglycemia in critical illness: a review.
Brealey D, Singer M. Brealey D, et al. Among authors: singer m. J Diabetes Sci Technol. 2009 Nov 1;3(6):1250-60. doi: 10.1177/193229680900300604. J Diabetes Sci Technol. 2009. PMID: 20144378 Free PMC article. Review.
So you want to be ... a critical care physician.
Brealey DA, Singer M. Brealey DA, et al. Among authors: singer m. Br J Hosp Med (Lond). 2010 Jun;71(6):M96. doi: 10.12968/hmed.2010.71.Sup6.48469. Br J Hosp Med (Lond). 2010. PMID: 20551887 No abstract available.
Trial of early, goal-directed resuscitation for septic shock.
Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM; ProMISe Trial Investigators. Mouncey PR, et al. Among authors: singer m. N Engl J Med. 2015 Apr 2;372(14):1301-11. doi: 10.1056/NEJMoa1500896. Epub 2015 Mar 17. N Engl J Med. 2015. PMID: 25776532 Free article. Clinical Trial.
Immunophenotyping patients with sepsis and underlying haematological malignancy reveals defects in monocyte and lymphocyte function.
Snow TAC, Serisier A, Brealey D, Singer M, Arulkumaran N; University College London Hospitals Critical Care Research Team. Snow TAC, et al. Among authors: singer m. Intensive Care Med Exp. 2024 Jan 11;12(1):3. doi: 10.1186/s40635-023-00578-4. Intensive Care Med Exp. 2024. PMID: 38206543 Free PMC article. No abstract available.
Early dynamic changes to monocytes following major surgery are associated with subsequent infections.
Snow TAC, Waller AV, Loye R, Ryckaert F, Cesar A, Saleem N, Roy R, Whittle J, Al-Hindawi A, Das A, Singer M, Brealey D, Arulkumaran N; University College London Hospitals Critical Care Research Team. Snow TAC, et al. Among authors: singer m. Front Immunol. 2024 Apr 9;15:1352556. doi: 10.3389/fimmu.2024.1352556. eCollection 2024. Front Immunol. 2024. PMID: 38655251 Free PMC article.
2,629 results