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Reproducing human and cross-species drug toxicities using a Liver-Chip.
Jang KJ, Otieno MA, Ronxhi J, Lim HK, Ewart L, Kodella KR, Petropolis DB, Kulkarni G, Rubins JE, Conegliano D, Nawroth J, Simic D, Lam W, Singer M, Barale E, Singh B, Sonee M, Streeter AJ, Manthey C, Jones B, Srivastava A, Andersson LC, Williams D, Park H, Barrile R, Sliz J, Herland A, Haney S, Karalis K, Ingber DE, Hamilton GA. Jang KJ, et al. Among authors: singer m. Sci Transl Med. 2019 Nov 6;11(517):eaax5516. doi: 10.1126/scitranslmed.aax5516. Sci Transl Med. 2019. PMID: 31694927
Evaluation of miR-122 and other biomarkers in distinct acute liver injury in rats.
Starckx S, Batheja A, Verheyen GR, Jonghe SD, Steemans K, Dijck BV, Singer M, Bogdan N, Snoeys J, Vinken P, Sasaki JC, Gompel JV, Guzzie-Peck P, Lampo A, Lammens L. Starckx S, et al. Among authors: singer m. Toxicol Pathol. 2013 Jul;41(5):795-804. doi: 10.1177/0192623312464436. Epub 2012 Nov 9. Toxicol Pathol. 2013. PMID: 23143187
Analytic evaluation of a human ELISA kit for measurement of inhibin B in rat samples.
Coulson M, Bickerton S, Betts CJ, Jacobsen M, Stewart J, Chapin RE, Reagan WJ, Alvey J, Erdos Z, Saldutti LP, Sonee M, Bogdan N, Singer M, Vinken P, Barlow V, Czajkowski K, Kim JH. Coulson M, et al. Among authors: singer m. Birth Defects Res B Dev Reprod Toxicol. 2013 Feb;98(1):4-16. doi: 10.1002/bdrb.21047. Epub 2013 Jan 24. Birth Defects Res B Dev Reprod Toxicol. 2013. PMID: 23349040
Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation.
Scannevin RH, Alexander R, Haarlander TM, Burke SL, Singer M, Huo C, Zhang YM, Maguire D, Spurlino J, Deckman I, Carroll KI, Lewandowski F, Devine E, Dzordzorme K, Tounge B, Milligan C, Bayoumy S, Williams R, Schalk-Hihi C, Leonard K, Jackson P, Todd M, Kuo LC, Rhodes KJ. Scannevin RH, et al. Among authors: singer m. J Biol Chem. 2017 Oct 27;292(43):17963-17974. doi: 10.1074/jbc.M117.806075. Epub 2017 Aug 31. J Biol Chem. 2017. PMID: 28860188 Free PMC article.
A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis.
Church RJ, Wu H, Mosedale M, Sumner SJ, Pathmasiri W, Kurtz CL, Pletcher MT, Eaddy JS, Pandher K, Singer M, Batheja A, Watkins PB, Adkins K, Harrill AH. Church RJ, et al. Among authors: singer m. Toxicol Sci. 2014 Aug 1;140(2):481-92. doi: 10.1093/toxsci/kfu094. Epub 2014 May 20. Toxicol Sci. 2014. PMID: 24848797 Free PMC article.
Diagnosing sepsis: where we're at and where we're going.
Zimmermann T, Brealey D, Singer M. Zimmermann T, et al. Among authors: singer m. Intensive Care Med. 2024 May 2. doi: 10.1007/s00134-024-07428-1. Online ahead of print. Intensive Care Med. 2024. PMID: 38695925 No abstract available.
2,629 results