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913 results

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AAV-Mediated CAG-Targeting Selectively Reduces Polyglutamine-Expanded Protein and Attenuates Disease Phenotypes in a Spinocerebellar Ataxia Mouse Model.
Niewiadomska-Cimicka A, Fievet L, Surdyka M, Jesion E, Keime C, Singer E, Eisenmann A, Kalinowska-Poska Z, Nguyen HHP, Fiszer A, Figiel M, Trottier Y. Niewiadomska-Cimicka A, et al. Among authors: singer e. Int J Mol Sci. 2024 Apr 15;25(8):4354. doi: 10.3390/ijms25084354. Int J Mol Sci. 2024. PMID: 38673939 Free PMC article.
Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma.
Choueiri TK, Tomczak P, Park SH, Venugopal B, Ferguson T, Symeonides SN, Hajek J, Chang YH, Lee JL, Sarwar N, Haas NB, Gurney H, Sawrycki P, Mahave M, Gross-Goupil M, Zhang T, Burke JM, Doshi G, Melichar B, Kopyltsov E, Alva A, Oudard S, Topart D, Hammers H, Kitamura H, McDermott DF, Silva A, Winquist E, Cornell J, Elfiky A, Burgents JE, Perini RF, Powles T; KEYNOTE-564 Investigators. Choueiri TK, et al. N Engl J Med. 2024 Apr 18;390(15):1359-1371. doi: 10.1056/NEJMoa2312695. N Engl J Med. 2024. PMID: 38631003 Clinical Trial.
Special populations in metastatic renal cell carcinoma.
Goodstein T, Goldberg I, Acikgoz Y, Hasanov E, Srinivasan R, Singer EA. Goodstein T, et al. Among authors: singer ea. Curr Opin Oncol. 2024 May 1;36(3):186-194. doi: 10.1097/CCO.0000000000001028. Epub 2024 Feb 23. Curr Opin Oncol. 2024. PMID: 38573208 Review.
HIV and COVID-19: two pandemics with significant (but different) central nervous system complications.
Magaki S, Zhang T, Han K, Hilda M, Yong WH, Achim C, Fishbein G, Fishbein MC, Garner O, Salamon N, Williams CK, Valdes-Sueiras MA, Hsu JJ, Kelesidis T, Mathisen GE, Lavretsky H, Singer EJ, Vinters HV. Magaki S, et al. Among authors: singer ej. Free Neuropathol. 2024 Mar 5;5:5-5. doi: 10.17879/freeneuropathology-2024-5343. eCollection 2024 Jan. Free Neuropathol. 2024. PMID: 38469363 Free PMC article.
Roles of Androgen Receptor Signaling in Urothelial Carcinoma.
Sundi D, Collier KA, Yang Y, Diaz DA, Pohar KS, Singer EA, Gupta S, Carson WE 3rd, Clinton SK, Li Z, Messing EM. Sundi D, et al. Among authors: singer ea. Cancers (Basel). 2024 Feb 10;16(4):746. doi: 10.3390/cancers16040746. Cancers (Basel). 2024. PMID: 38398136 Free PMC article. Review.
Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability.
Mulato A, Lansdon E, Aoyama R, Voigt J, Lee M, Liclican A, Lee G, Singer E, Stafford B, Gong R, Murray B, Chan J, Lee J, Xu Y, Ahmadyar S, Gonzalez A, Cho A, Stepan GJ, Schmitz U, Schultz B, Marchand B, Brumshtein B, Wang R, Yu H, Cihlar T, Xu L, Yant SR. Mulato A, et al. Among authors: singer e. Antimicrob Agents Chemother. 2024 Apr 3;68(4):e0137323. doi: 10.1128/aac.01373-23. Epub 2024 Feb 21. Antimicrob Agents Chemother. 2024. PMID: 38380945 Free PMC article.
913 results