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Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia.
Grant RA, Morales-Nebreda L, Markov NS, Swaminathan S, Querrey M, Guzman ER, Abbott DA, Donnelly HK, Donayre A, Goldberg IA, Klug ZM, Borkowski N, Lu Z, Kihshen H, Politanska Y, Sichizya L, Kang M, Shilatifard A, Qi C, Lomasney JW, Argento AC, Kruser JM, Malsin ES, Pickens CO, Smith SB, Walter JM, Pawlowski AE, Schneider D, Nannapaneni P, Abdala-Valencia H, Bharat A, Gottardi CJ, Budinger GRS, Misharin AV, Singer BD, Wunderink RG; NU SCRIPT Study Investigators. Grant RA, et al. Among authors: singer bd. Nature. 2021 Feb;590(7847):635-641. doi: 10.1038/s41586-020-03148-w. Epub 2021 Jan 11. Nature. 2021. PMID: 33429418 Free PMC article.
Transcriptomic signatures decode Th17 cell pathogenicity.
Reyfman PA, Bartom ET, Singer BD. Reyfman PA, et al. Among authors: singer bd. Cell Mol Immunol. 2016 Sep;13(5):557-9. doi: 10.1038/cmi.2016.22. Epub 2016 May 2. Cell Mol Immunol. 2016. PMID: 27133470 Free PMC article. No abstract available.
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span.
Misharin AV, Morales-Nebreda L, Reyfman PA, Cuda CM, Walter JM, McQuattie-Pimentel AC, Chen CI, Anekalla KR, Joshi N, Williams KJN, Abdala-Valencia H, Yacoub TJ, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Gates K, Lam AP, Nicholson TT, Homan PJ, Soberanes S, Dominguez S, Morgan VK, Saber R, Shaffer A, Hinchcliff M, Marshall SA, Bharat A, Berdnikovs S, Bhorade SM, Bartom ET, Morimoto RI, Balch WE, Sznajder JI, Chandel NS, Mutlu GM, Jain M, Gottardi CJ, Singer BD, Ridge KM, Bagheri N, Shilatifard A, Budinger GRS, Perlman H. Misharin AV, et al. Among authors: singer bd. J Exp Med. 2017 Aug 7;214(8):2387-2404. doi: 10.1084/jem.20162152. Epub 2017 Jul 10. J Exp Med. 2017. PMID: 28694385 Free PMC article.
Metastatic pulmonary calcification and end-stage renal disease.
Walter JM, Stanley M, Singer BD. Walter JM, et al. Among authors: singer bd. Cleve Clin J Med. 2017 Sep;84(9):668-669. doi: 10.3949/ccjm.84a.16132. Cleve Clin J Med. 2017. PMID: 28885910 Free PMC article. No abstract available.
DNA methylation regulates the neonatal CD4+ T-cell response to pneumonia in mice.
McGrath-Morrow SA, Ndeh R, Helmin KA, Chen SY, Anekalla KR, Abdala-Valencia H, D'Alessio FR, Collaco JM, Singer BD. McGrath-Morrow SA, et al. Among authors: singer bd. J Biol Chem. 2018 Jul 27;293(30):11772-11783. doi: 10.1074/jbc.RA118.003589. Epub 2018 Jun 4. J Biol Chem. 2018. PMID: 29866884 Free PMC article.
DNA methylation as a transcriptional regulator of the immune system.
Morales-Nebreda L, McLafferty FS, Singer BD. Morales-Nebreda L, et al. Among authors: singer bd. Transl Res. 2019 Feb;204:1-18. doi: 10.1016/j.trsl.2018.08.001. Epub 2018 Aug 9. Transl Res. 2019. PMID: 30170004 Free PMC article. Review.
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