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Spatiotemporal genomic profiling of intestinal metaplasia reveals clonal dynamics of gastric cancer progression.
Huang KK, Ma H, Chong RHH, Uchihara T, Lian BSX, Zhu F, Sheng T, Srivastava S, Tay ST, Sundar R, Tan ALK, Ong X, Lee M, Ho SWT, Lesluyes T, Ashktorab H, Smoot D, Van Loo P, Chua JS, Ramnarayanan K, Lau LHS, Gotoda T, Kim HS, Ang TL, Khor C, Lee JWJ, Tsao SKK, Yang WL, Teh M, Chung H, So JBY, Yeoh KG, Tan P; Singapore Gastric Cancer Consortium. Huang KK, et al. Cancer Cell. 2023 Dec 11;41(12):2019-2037.e8. doi: 10.1016/j.ccell.2023.10.004. Epub 2023 Oct 26. Cancer Cell. 2023. PMID: 37890493 Free PMC article.
Comprehensive molecular phenotyping of ARID1A-deficient gastric cancer reveals pervasive epigenomic reprogramming and therapeutic opportunities.
Xu C, Huang KK, Law JH, Chua JS, Sheng T, Flores NM, Pizzi MP, Okabe A, Tan ALK, Zhu F, Kumar V, Lu X, Benitez AM, Lian BSX, Ma H, Ho SWT, Ramnarayanan K, Anene-Nzelu CG, Razavi-Mohseni M, Abdul Ghani SAB, Tay ST, Ong X, Lee MH, Guo YA, Ashktorab H, Smoot D, Li S, Skanderup AJ, Beer MA, Foo RSY, Wong JSH, Sanghvi K, Yong WP, Sundar R, Kaneda A, Prabhakar S, Mazur PK, Ajani JA, Yeoh KG, So JB, Tan P; Singapore Gastric Cancer Consortium. Xu C, et al. Gut. 2023 Sep;72(9):1651-1663. doi: 10.1136/gutjnl-2022-328332. Epub 2023 Mar 14. Gut. 2023. PMID: 36918265
"3G" Trial: An RNA Editing Signature to Guide Gastric Cancer Chemotherapy.
An O, Song Y, Ke X, So JB, Sundar R, Yang H, Rha SY, Lee MH, Tay ST, Ong X, Tan ALK, Ng MCH, Tantoso E, Chen L, Tan P, Yong WP; Singapore Gastric Cancer Consortium (SGCC). An O, et al. Cancer Res. 2021 May 15;81(10):2788-2798. doi: 10.1158/0008-5472.CAN-20-2872. Epub 2021 Feb 8. Cancer Res. 2021. PMID: 33558338
Clinical and therapeutic relevance of PIM1 kinase in gastric cancer.
Yan B, Yau EX, Samanta S, Ong CW, Yong KJ, Ng LK, Bhattacharya B, Lim KH, Soong R, Yeoh KG, Deng N, Tan P, Lam Y, Salto-Tellez M; Singapore Gastric Cancer Consortium. Yan B, et al. Gastric Cancer. 2012 Apr;15(2):188-97. doi: 10.1007/s10120-011-0097-2. Epub 2011 Oct 13. Gastric Cancer. 2012. PMID: 21993851
Real-Time Tumor Gene Expression Profiling to Direct Gastric Cancer Chemotherapy: Proof-of-Concept "3G" Trial.
Yong WP, Rha SY, Tan IB, Choo SP, Syn NL, Koh V, Tan SH, Asuncion BR, Sundar R, So JB, Shabbir A, Tan CS, Kim HS, Jung M, Chung HC, Ng MCH, Tai DW, Lee MH, Wu J, Yeoh KG, Tan P; Singapore Gastric Cancer Consortium (SGCC). Yong WP, et al. Clin Cancer Res. 2018 Nov 1;24(21):5272-5281. doi: 10.1158/1078-0432.CCR-18-0193. Epub 2018 Jul 25. Clin Cancer Res. 2018. PMID: 30045931 Clinical Trial.
Ligand-mediated PAI-1 inhibition in a mouse model of peritoneal carcinomatosis.
Hendrikson J, Liu Y, Ng WH, Lee JY, Lim AH, Loh JW, Ng CCY, Ong WS, Tan JW, Tan QX, Ng G, Shannon NB, Lim WK, Lim TKH, Chua C, Wong JSM, Tan GHC, So JBY, Yeoh KG, Teh BT, Chia CS, Soo KC, Kon OL, Tan IB, Chan JY, Teo MCC, Ong CJ; Singapore Peritoneal Oncology Study (SPOS) Group and Singapore Gastric Cancer Consortium (SGCC). Hendrikson J, et al. Cell Rep Med. 2022 Feb 15;3(2):100526. doi: 10.1016/j.xcrm.2022.100526. eCollection 2022 Feb 15. Cell Rep Med. 2022. PMID: 35243423 Free PMC article.
MicroRNA-130b regulates the tumour suppressor RUNX3 in gastric cancer.
Lai KW, Koh KX, Loh M, Tada K, Subramaniam MM, Lim XY, Vaithilingam A, Salto-Tellez M, Iacopetta B, Ito Y, Soong R; Singapore Gastric Cancer Consortium. Lai KW, et al. Eur J Cancer. 2010 May;46(8):1456-63. doi: 10.1016/j.ejca.2010.01.036. Epub 2010 Feb 20. Eur J Cancer. 2010. PMID: 20176475