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Binding of an acceptor substrate analog enhances the enzymatic activity of human blood group B galactosyltransferase.
Glycobiology. 2010 Jun;20(6):718-23. doi: 10.1093/glycob/cwq019. Epub 2010 Feb 12.
Glycobiology. 2010.
PMID: 20154292
NMR-based exploration of the acceptor binding site of human blood group B galactosyltransferase with molecular fragments.
Rademacher C, Landström J, Sindhuwinata N, Palcic MM, Widmalm G, Peters T.
Rademacher C, et al. Among authors: sindhuwinata n.
Glycoconj J. 2010 Apr;27(3):349-58. doi: 10.1007/s10719-010-9282-5. Epub 2010 Mar 9.
Glycoconj J. 2010.
PMID: 20217221
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A nonionic inhibitor with high specificity for the UDP-Gal donor binding site of human blood group B galactosyltransferase: design, synthesis, and characterization.
Schaefer K, Sindhuwinata N, Hackl T, Kötzler MP, Niemeyer FC, Palcic MM, Peters T, Meyer B.
Schaefer K, et al. Among authors: sindhuwinata n.
J Med Chem. 2013 Mar 14;56(5):2150-4. doi: 10.1021/jm300642a. Epub 2013 Feb 28.
J Med Chem. 2013.
PMID: 23406460
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Thermodynamic signature of substrates and substrate analogs binding to human blood group B galactosyltransferase from isothermal titration calorimetry experiments.
Sindhuwinata N, Grimm LL, Weißbach S, Zinn S, Munoz E, Palcic MM, Peters T.
Sindhuwinata N, et al.
Biopolymers. 2013 Oct;99(10):784-95. doi: 10.1002/bip.22297.
Biopolymers. 2013.
PMID: 23754468
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High-resolution crystal structures and STD NMR mapping of human ABO(H) blood group glycosyltransferases in complex with trisaccharide reaction products suggest a molecular basis for product release.
Gagnon SML, Legg MSG, Sindhuwinata N, Letts JA, Johal AR, Schuman B, Borisova SN, Palcic MM, Peters T, Evans SV.
Gagnon SML, et al. Among authors: sindhuwinata n.
Glycobiology. 2017 Oct 1;27(10):966-977. doi: 10.1093/glycob/cwx053.
Glycobiology. 2017.
PMID: 28575295
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A new concept for glycosyltransferase inhibitors: nonionic mimics of the nucleotide donor of the human blood group B galactosyltransferase.
Schaefer K, Albers J, Sindhuwinata N, Peters T, Meyer B.
Schaefer K, et al. Among authors: sindhuwinata n.
Chembiochem. 2012 Feb 13;13(3):443-50. doi: 10.1002/cbic.201100642. Epub 2012 Jan 5.
Chembiochem. 2012.
PMID: 22223604
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A glycosyltransferase inhibitor from a molecular fragment library simultaneously interferes with metal ion and substrate binding.
Jørgensen R, Grimm LL, Sindhuwinata N, Peters T, Palcic MM.
Jørgensen R, et al. Among authors: sindhuwinata n.
Angew Chem Int Ed Engl. 2012 Apr 23;51(17):4171-5. doi: 10.1002/anie.201108345. Epub 2012 Mar 8.
Angew Chem Int Ed Engl. 2012.
PMID: 22407594
No abstract available.
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