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Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.
Lecoutey C, Hedou D, Freret T, Giannoni P, Gaven F, Since M, Bouet V, Ballandonne C, Corvaisier S, Malzert Fréon A, Mignani S, Cresteil T, Boulouard M, Claeysen S, Rochais C, Dallemagne P. Lecoutey C, et al. Among authors: since m. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3825-30. doi: 10.1073/pnas.1410315111. Epub 2014 Aug 25. Proc Natl Acad Sci U S A. 2014. PMID: 25157130 Free PMC article.
Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer's disease.
Toublet FX, Lalut J, Hatat B, Lecoutey C, Davis A, Since M, Corvaisier S, Freret T, Sopková-de Oliveira Santos J, Claeysen S, Boulouard M, Dallemagne P, Rochais C. Toublet FX, et al. Among authors: since m. Eur J Med Chem. 2021 Jan 15;210:113059. doi: 10.1016/j.ejmech.2020.113059. Epub 2020 Dec 3. Eur J Med Chem. 2021. PMID: 33310288
Novel thienopyrimidones targeting hepatic and erythrocytic stages of Plasmodium parasites with increased microsomal stability.
Lagardère P, Mustière R, Amanzougaghene N, Hutter S, Casanova M, Franetich JF, Tajeri S, Malzert-Fréon A, Corvaisier S, Since M, Azas N, Vanelle P, Verhaeghe P, Primas N, Mazier D, Masurier N, Lisowski V. Lagardère P, et al. Among authors: since m. Eur J Med Chem. 2023 Dec 5;261:115873. doi: 10.1016/j.ejmech.2023.115873. Epub 2023 Oct 13. Eur J Med Chem. 2023. PMID: 37857143
29 results