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Upregulation of the ERRγ-VDAC1 axis underlies the molecular pathogenesis of pancreatitis.
Chanda D, Thoudam T, Sinam IS, Lim CW, Kim M, Wang J, Lee KM, Ma J, Saxena R, Choi J, Oh CJ, Lee H, Jeon YH, Cho SJ, Jung HY, Park KG, Choi HS, Suh JM, Auwerx J, Ji B, Liangpunsakul S, Jeon JH, Lee IK. Chanda D, et al. Among authors: sinam is. Proc Natl Acad Sci U S A. 2023 May 16;120(20):e2219644120. doi: 10.1073/pnas.2219644120. Epub 2023 May 8. Proc Natl Acad Sci U S A. 2023. PMID: 37155882 Free PMC article.
Enhanced Ca2+-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease.
Thoudam T, Chanda D, Lee JY, Jung MK, Sinam IS, Kim BG, Park BY, Kwon WH, Kim HJ, Kim M, Lim CW, Lee H, Huh YH, Miller CA, Saxena R, Skill NJ, Huda N, Kusumanchi P, Ma J, Yang Z, Kim MJ, Mun JY, Harris RA, Jeon JH, Liangpunsakul S, Lee IK. Thoudam T, et al. Among authors: sinam is. Nat Commun. 2023 Mar 27;14(1):1703. doi: 10.1038/s41467-023-37214-4. Nat Commun. 2023. PMID: 36973273 Free PMC article.
Noncanonical PDK4 action alters mitochondrial dynamics to affect the cellular respiratory status.
Thoudam T, Chanda D, Sinam IS, Kim BG, Kim MJ, Oh CJ, Lee JY, Kim MJ, Park SY, Lee SY, Jung MK, Mun JY, Harris RA, Ishihara N, Jeon JH, Lee IK. Thoudam T, et al. Among authors: sinam is. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2120157119. doi: 10.1073/pnas.2120157119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969774 Free PMC article.