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A pharmacological toolkit for human microglia identifies Topoisomerase I inhibitors as immunomodulators for Alzheimer's disease.
Haage V, Tuddenham JF, Comandante-Lou N, Bautista A, Monzel A, Chiu R, Fujita M, Garcia FG, Bhattarai P, Patel R, Buonfiglioli A, Idiarte J, Herman M, Rinderspacher A, Mela A, Zhao W, Argenziano MG, Furnari JL, Banu MA, Landry DW, Bruce JN, Canoll P, Zhang Y, Nuriel T, Kizil C, Sproul AA, de Witte LD, Sims PA, Menon V, Picard M, De Jager PL. Haage V, et al. Among authors: sims pa. bioRxiv [Preprint]. 2024 Feb 6:2024.02.06.579103. doi: 10.1101/2024.02.06.579103. bioRxiv. 2024. PMID: 38370689 Free PMC article. Preprint.
Glioma-Induced Alterations in Excitatory Neurons are Reversed by mTOR Inhibition.
Goldberg AR, Dovas A, Torres D, Sharma SD, Mela A, Merricks EM, Olabarria M, Shokooh LA, Zhao HT, Kotidis C, Calvaresi P, Viswanathan A, Banu MA, Razavilar A, Sudhakar TD, Saxena A, Chokran C, Humala N, Mahajan A, Xu W, Metz JB, Chen C, Bushong EA, Boassa D, Ellisman MH, Hillman EMC, McKhann GM 2nd, Gill BJA, Rosenfeld SS, Schevon CA, Bruce JN, Sims PA, Peterka DS, Canoll P. Goldberg AR, et al. Among authors: sims pa. bioRxiv [Preprint]. 2024 Jan 21:2024.01.10.575092. doi: 10.1101/2024.01.10.575092. bioRxiv. 2024. PMID: 38293120 Free PMC article. Preprint.
Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age.
Wells SB, Rainbow DB, Mark M, Szabo PA, Ergen C, Maceiras AR, Caron DP, Rahmani E, Benuck E, Amiri VVP, Chen D, Wagner A, Howlett SK, Jarvis LB, Ellis KL, Kubota M, Matsumoto R, Mahbubani K, Saeb-Parsy K, Dominguez-Conde C, Richardson L, Xu C, Li S, Mamanova L, Bolt L, Wilk A, Teichmann SA, Farber DL, Sims PA, Jones JL, Yosef N. Wells SB, et al. Among authors: sims pa. bioRxiv [Preprint]. 2024 Jan 4:2024.01.03.573877. doi: 10.1101/2024.01.03.573877. bioRxiv. 2024. PMID: 38260588 Free PMC article. Preprint.
Isolated Ulnar Neuropathy After Acute Angioedema.
Itani S, Malick H, Nangrani PC, Lai T, Sims P. Itani S, et al. Among authors: sims p. Cureus. 2023 Sep 7;15(9):e44872. doi: 10.7759/cureus.44872. eCollection 2023 Sep. Cureus. 2023. PMID: 37814739 Free PMC article.
Induction of bronchus-associated lymphoid tissue is an early life adaptation for promoting human B cell immunity.
Matsumoto R, Gray J, Rybkina K, Oppenheimer H, Levy L, Friedman LM, Khamaisi M, Meng W, Rosenfeld AM, Guyer RS, Bradley MC, Chen D, Atkinson MA, Brusko TM, Brusko M, Connors TJ, Luning Prak ET, Hershberg U, Sims PA, Hertz T, Farber DL. Matsumoto R, et al. Among authors: sims pa. Nat Immunol. 2023 Aug;24(8):1370-1381. doi: 10.1038/s41590-023-01557-3. Epub 2023 Jul 17. Nat Immunol. 2023. PMID: 37460638 Free PMC article.
620 results