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RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells.
Chen F, Gurler SB, Novo D, Selli C, Alferez DG, Eroglu S, Pavlou K, Zhang J, Sims AH, Humphreys NE, Adamson A, Campbell A, Sansom OJ, Tournier C, Clarke RB, Brennan K, Streuli CH, Ucar A. Chen F, et al. Among authors: sims ah. Oncogene. 2023 Feb;42(9):679-692. doi: 10.1038/s41388-022-02574-6. Epub 2023 Jan 5. Oncogene. 2023. PMID: 36599922 Free PMC article.
Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity.
Simões BM, O'Brien CS, Eyre R, Silva A, Yu L, Sarmiento-Castro A, Alférez DG, Spence K, Santiago-Gómez A, Chemi F, Acar A, Gandhi A, Howell A, Brennan K, Rydén L, Catalano S, Andó S, Gee J, Ucar A, Sims AH, Marangoni E, Farnie G, Landberg G, Howell SJ, Clarke RB. Simões BM, et al. Among authors: sims ah. Cell Rep. 2015 Sep 29;12(12):1968-77. doi: 10.1016/j.celrep.2015.08.050. Epub 2015 Sep 17. Cell Rep. 2015. PMID: 26387946 Free PMC article.
Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer.
Simões BM, Santiago-Gómez A, Chiodo C, Moreira T, Conole D, Lovell S, Alferez D, Eyre R, Spence K, Sarmiento-Castro A, Kohler B, Morisset L, Lanzino M, Andò S, Marangoni E, Sims AH, Tate EW, Howell SJ, Clarke RB. Simões BM, et al. Among authors: sims ah. Oncogene. 2020 Jun;39(25):4896-4908. doi: 10.1038/s41388-020-1335-z. Epub 2020 May 30. Oncogene. 2020. PMID: 32472077 Free PMC article.
117 results