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MYC sensitises cells to apoptosis by driving energetic demand.
Edwards-Hicks J, Su H, Mangolini M, Yoneten KK, Wills J, Rodriguez-Blanco G, Young C, Cho K, Barker H, Muir M, Guerrieri AN, Li XF, White R, Manasterski P, Mandrou E, Wills K, Chen J, Abraham E, Sateri K, Qian BZ, Bankhead P, Arends M, Gammoh N, von Kriegsheim A, Patti GJ, Sims AH, Acosta JC, Brunton V, Kranc KR, Christophorou M, Pearce EL, Ringshausen I, Finch AJ. Edwards-Hicks J, et al. Among authors: sims ah. Nat Commun. 2022 Aug 9;13(1):4674. doi: 10.1038/s41467-022-32368-z. Nat Commun. 2022. PMID: 35945217 Free PMC article.
Trastuzumab and pertuzumab produce changes in morphology and estrogen receptor signaling in ovarian cancer xenografts revealing new treatment strategies.
Faratian D, Zweemer AJ, Nagumo Y, Sims AH, Muir M, Dodds M, Mullen P, Um I, Kay C, Hasmann M, Harrison DJ, Langdon SP. Faratian D, et al. Among authors: sims ah. Clin Cancer Res. 2011 Jul 1;17(13):4451-61. doi: 10.1158/1078-0432.CCR-10-2461. Epub 2011 May 13. Clin Cancer Res. 2011. PMID: 21571868 Free article.
Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity.
Serrels A, Lund T, Serrels B, Byron A, McPherson RC, von Kriegsheim A, Gómez-Cuadrado L, Canel M, Muir M, Ring JE, Maniati E, Sims AH, Pachter JA, Brunton VG, Gilbert N, Anderton SM, Nibbs RJ, Frame MC. Serrels A, et al. Among authors: sims ah. Cell. 2015 Sep 24;163(1):160-73. doi: 10.1016/j.cell.2015.09.001. Cell. 2015. PMID: 26406376 Free PMC article.
Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis.
Sarvi S, Patel H, Li J, Dodd GL, Creedon H, Muir M, Ward J, Dawson JC, Lee M, Culley J, Salter DM, Sims AH, Byron A, Brunton VG. Sarvi S, et al. Among authors: sims ah. Cancer Res. 2018 Mar 15;78(6):1484-1496. doi: 10.1158/0008-5472.CAN-17-1518. Epub 2018 Jan 12. Cancer Res. 2018. PMID: 29330144 Free PMC article.
Development of mouse models of angiosarcoma driven by p53.
Salter DM, Griffin M, Muir M, Teo K, Culley J, Smith JR, Gomez-Cuadrado L, Matchett K, Sims AH, Hayward L, Henderson NC, Brunton VG. Salter DM, et al. Among authors: sims ah. Dis Model Mech. 2019 Jul 9;12(7):dmm038612. doi: 10.1242/dmm.038612. Dis Model Mech. 2019. PMID: 31221668 Free PMC article.
Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling.
Eyre R, Alférez DG, Santiago-Gómez A, Spence K, McConnell JC, Hart C, Simões BM, Lefley D, Tulotta C, Storer J, Gurney A, Clarke N, Brown M, Howell SJ, Sims AH, Farnie G, Ottewell PD, Clarke RB. Eyre R, et al. Among authors: sims ah. Nat Commun. 2019 Nov 1;10(1):5016. doi: 10.1038/s41467-019-12807-0. Nat Commun. 2019. PMID: 31676788 Free PMC article.
118 results