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Intestinal inflammation targets cancer-inducing activity of the microbiota.
Arthur JC, Perez-Chanona E, Mühlbauer M, Tomkovich S, Uronis JM, Fan TJ, Campbell BJ, Abujamel T, Dogan B, Rogers AB, Rhodes JM, Stintzi A, Simpson KW, Hansen JJ, Keku TO, Fodor AA, Jobin C. Arthur JC, et al. Among authors: simpson kw. Science. 2012 Oct 5;338(6103):120-3. doi: 10.1126/science.1224820. Epub 2012 Aug 16. Science. 2012. PMID: 22903521 Free PMC article.
Yersiniabactin-Producing Adherent/Invasive Escherichia coli Promotes Inflammation-Associated Fibrosis in Gnotobiotic Il10-/- Mice.
Ellermann M, Gharaibeh RZ, Fulbright L, Dogan B, Moore LN, Broberg CA, Lopez LR, Rothemich AM, Herzog JW, Rogala A, Gordon IO, Rieder F, Brouwer CR, Simpson KW, Jobin C, Sartor RB, Arthur JC. Ellermann M, et al. Among authors: simpson kw. Infect Immun. 2019 Oct 18;87(11):e00587-19. doi: 10.1128/IAI.00587-19. Print 2019 Nov. Infect Immun. 2019. PMID: 31481410 Free PMC article.
Inflammation-associated adherent-invasive Escherichia coli are enriched in pathways for use of propanediol and iron and M-cell translocation.
Dogan B, Suzuki H, Herlekar D, Sartor RB, Campbell BJ, Roberts CL, Stewart K, Scherl EJ, Araz Y, Bitar PP, Lefébure T, Chandler B, Schukken YH, Stanhope MJ, Simpson KW. Dogan B, et al. Among authors: simpson kw. Inflamm Bowel Dis. 2014 Nov;20(11):1919-32. doi: 10.1097/MIB.0000000000000183. Inflamm Bowel Dis. 2014. PMID: 25230163
Murine Adherent and Invasive E. coli Induces Chronic Inflammation and Immune Responses in the Small and Large Intestines of Monoassociated IL-10-/- Mice Independent of Long Polar Fimbriae Adhesin A.
Schmitz JM, Tonkonogy SL, Dogan B, Leblond A, Whitehead KJ, Kim SC, Simpson KW, Sartor RB. Schmitz JM, et al. Among authors: simpson kw. Inflamm Bowel Dis. 2019 Apr 11;25(5):875-885. doi: 10.1093/ibd/izy386. Inflamm Bowel Dis. 2019. PMID: 30576451 Free PMC article.
Dietary Fructose Alters the Composition, Localization, and Metabolism of Gut Microbiota in Association With Worsening Colitis.
Montrose DC, Nishiguchi R, Basu S, Staab HA, Zhou XK, Wang H, Meng L, Johncilla M, Cubillos-Ruiz JR, Morales DK, Wells MT, Simpson KW, Zhang S, Dogan B, Jiao C, Fei Z, Oka A, Herzog JW, Sartor RB, Dannenberg AJ. Montrose DC, et al. Among authors: simpson kw. Cell Mol Gastroenterol Hepatol. 2021;11(2):525-550. doi: 10.1016/j.jcmgh.2020.09.008. Epub 2020 Sep 20. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32961355 Free PMC article.
Mucosal metabolites fuel the growth and virulence of E. coli linked to Crohn's disease.
Zhang S, Morgan X, Dogan B, Martin FP, Strickler S, Oka A, Herzog J, Liu B, Dowd SE, Huttenhower C, Pichaud M, Dogan EI, Satsangi J, Longman R, Yantiss R, Mueller LA, Scherl EJ, Sartor RB, Simpson KW. Zhang S, et al. Among authors: simpson kw. JCI Insight. 2022 May 23;7(10):e157013. doi: 10.1172/jci.insight.157013. JCI Insight. 2022. PMID: 35413017 Free PMC article.
IgA-coated E. coli enriched in Crohn's disease spondyloarthritis promote TH17-dependent inflammation.
Viladomiu M, Kivolowitz C, Abdulhamid A, Dogan B, Victorio D, Castellanos JG, Woo V, Teng F, Tran NL, Sczesnak A, Chai C, Kim M, Diehl GE, Ajami NJ, Petrosino JF, Zhou XK, Schwartzman S, Mandl LA, Abramowitz M, Jacob V, Bosworth B, Steinlauf A, Scherl EJ, Wu HJ, Simpson KW, Longman RS. Viladomiu M, et al. Among authors: simpson kw. Sci Transl Med. 2017 Feb 8;9(376):eaaf9655. doi: 10.1126/scitranslmed.aaf9655. Sci Transl Med. 2017. PMID: 28179509 Free PMC article.
160 results