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Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism.
Lancaster MS, Kim B, Doud EH, Tate MD, Sharify AD, Gao H, Chen D, Simpson E, Gillespie P, Chu X, Miller MJ, Wang Y, Liu Y, Mosley AL, Kim J, Graham BH. Lancaster MS, et al. Among authors: simpson e. Cell Rep. 2023 Oct 31;42(10):113241. doi: 10.1016/j.celrep.2023.113241. Epub 2023 Oct 17. Cell Rep. 2023. PMID: 37819759 Free PMC article.
Upregulation of lipid metabolism genes in the breast prior to cancer diagnosis.
Marino N, German R, Rao X, Simpson E, Liu S, Wan J, Liu Y, Sandusky G, Jacobsen M, Stoval M, Cao S, Storniolo AMV. Marino N, et al. Among authors: simpson e. NPJ Breast Cancer. 2020 Oct 6;6:50. doi: 10.1038/s41523-020-00191-8. eCollection 2020. NPJ Breast Cancer. 2020. PMID: 33083529 Free PMC article.
Prostaglandin E2 Enhances Aged Hematopoietic Stem Cell Function.
Patterson AM, Plett PA, Sampson CH, Simpson E, Liu Y, Pelus LM, Orschell CM. Patterson AM, et al. Among authors: simpson e. Stem Cell Rev Rep. 2021 Oct;17(5):1840-1854. doi: 10.1007/s12015-021-10177-z. Epub 2021 May 11. Stem Cell Rev Rep. 2021. PMID: 33974233
Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.
Kumar B, Adebayo AK, Prasad M, Capitano ML, Wang R, Bhat-Nakshatri P, Anjanappa M, Simpson E, Chen D, Liu Y, Schilder JM, Colter AB, Maguire C, Temm CJ, Sandusky G, Doud EH, Wijeratne AB, Mosley AL, Broxmeyer HE, Nakshatri H. Kumar B, et al. Among authors: simpson e. Sci Adv. 2022 Jan 14;8(2):eabh3375. doi: 10.1126/sciadv.abh3375. Epub 2022 Jan 12. Sci Adv. 2022. PMID: 35020422 Free PMC article.
2,070 results